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HaloPROTAC3

Catalog No. T32043 CAS 1799506-07-2

Synonyms: Halo PROTAC-3, HaloPROTAC 3, HaloPROTAC-3

HaloPROTAC3 (HaloPROTAC-3) is a conjugate of ligands for E3 and 16-atom-length linker and a degrader of HaloTag fusion proteins.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

HaloPROTAC3, CAS 1799506-07-2

Pack Size	Availability	Price/USD
1 mg	In stock	$ 112.00
5 mg	In stock	$ 278.00
10 mg	In stock	$ 455.00
25 mg	In stock	$ 753.00
50 mg	In stock	$ 1,060.00
100 mg	In stock	$ 1,430.00

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Purity: 95.44%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	HaloPROTAC3 (HaloPROTAC-3) is a conjugate of ligands for E3 and 16-atom-length linker and a degrader of HaloTag fusion proteins.
In vitro	HaloPROTAC 3 is an efficacious GFP-HaloTag7 degrader (DC50 = 19 nM). HaloPROTAC 3(625 nM) induces 90 % degradation of GFP-Halotag. HaloPROTAC 3 binds to VHL with an IC50 of 0.54 μM[1].

Synonyms	Halo PROTAC-3, HaloPROTAC 3, HaloPROTAC-3
Molecular Weight	799.42
Formula	C41H55ClN4O8S
CAS No.	1799506-07-2

Storage

keep away from direct sunlight

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Buckley DL, et al. HaloPROTACS: Use of Small Molecule PROTACs to Induce Degradation of HaloTag Fusion Proteins. ACS Chem Biol. 2015 Aug 21;10(8):1831-7.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

HaloPROTAC3 1799506-07-2 PROTAC Ligand for E3 Ligase Halo PROTAC-3 HaloPROTAC 3 HaloPROTAC-3 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.