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Argireline

Catalog No. TP1253 CAS 616204-22-9

Synonyms: Acetyl hexapeptide-3

Argireline (Acetyl hexapeptide-3) (Acetyl hexapeptide-3) is composed of chains of amino acids known as peptides. Argireline significantly inhibits Ca2+ dependent neurotransmitter release (acetylcholine) at the neuromuscular junction. Argireline has antiwrinkle and anti-aging activity[1][2][3].

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Argireline, CAS 616204-22-9

Pack Size	Availability	Price/USD
5 mg	In stock	$ 48.00
10 mg	In stock	$ 58.00
50 mg	In stock	$ 67.00
100 mg	In stock	$ 108.00

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Argireline (Acetyl hexapeptide-3) (Acetyl hexapeptide-3) is composed of chains of amino acids known as peptides. Argireline significantly inhibits Ca2+ dependent neurotransmitter release (acetylcholine) at the neuromuscular junction. Argireline has antiwrinkle and anti-aging activity[1][2][3].
In vitro	The incubation of Argireline solution in different concentrations with human embryonic kidney HEK-293 (IC50 of 34.862 μM) and neuroblastoma IMR-32 cells (IC50 of 68.458 μM)) for 48 h have dose dependent antiproliferative effect. Argireline solution incubated in different concentrations with HSF has a dose-dependent antiproliferative effect on those cells. Argireline in low concentration do not affect cell proliferation[2].
In vivo	Argireline was administered topically to elderly mice twice daily for six weeks, resulting in notable histological improvements in skin tissue. Specifically, the quantity of type I collagen fibers increased significantly (P < 0.01), and the amount of type III collagen fibers decreased (P < 0.05). This demonstrates Argireline's capability to enhance the histological architecture of skin tissue and restore aged skin[3].

Synonyms	Acetyl hexapeptide-3
Molecular Weight	888.99
Formula	C34H60N14O12S
CAS No.	616204-22-9

Storage

keep away from moisture

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 10mM

References and Literature

1. Blanes-Mira C, et al. A synthetic hexapeptide (Argireline) with antiwrinkle activity. Int J Cosmet Sci. 2002 Oct;24(5):303-10.

Related compound libraries

This product is contained In the following compound libraries：

Drug Repurposing Compound Library Peptide Compound Library Clinical Compound Library Anti-Aging Compound Library Bioactive Compounds Library Max Bioactive Compound Library NO PAINS Compound Library

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Keywords

Argireline 616204-22-9 Others skin-permeable Acetyl hexapeptide-3 BoNTs inhibit neurotransmitter Inhibitor peptide Acetyl hexapeptide 3 non-toxic Antiwrinkle anti-aging short-chain Acetyl hexapeptide3 inhibitor

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