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Anecortave Acetate

Catalog No. T21452 CAS 7753-60-8

Synonyms: Retaane, Al 3789, NSC 24345, NSC 15475, Anecortave

Anecortave Acetate (NSC-24345), an angiostatic steroid, is used for proteomics research.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Anecortave Acetate, CAS 7753-60-8

Pack Size	Availability	Price/USD
5 mg	In stock	$ 50.00
10 mg	In stock	$ 70.00
25 mg	In stock	$ 114.00
50 mg	In stock	$ 167.00
100 mg	In stock	$ 248.00
500 mg	In stock	$ 535.00

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Purity: 98.93%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Anecortave Acetate (NSC-24345), an angiostatic steroid, is used for proteomics research.

Synonyms	Retaane, Al 3789, NSC 24345, NSC 15475, Anecortave
Molecular Weight	386.48
Formula	C23H30O5
CAS No.	7753-60-8

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: Insoluble

DMSO: < 1mg/ml (insoluble）

References and Literature

1. Shepard AR, Conrow RE, Pang IH, Jacobson N, Rezwan M, Rutschmann K, Auerbach D, Sriramaratnam R, Cornish VW. Identification of PDE6D as a molecular target of anecortave acetate via a methotrexate-anchored yeast three-hybrid screen. ACS Chem Biol. 2013 Mar 15;8(3):549-58. doi: 10.1021/cb300296m. 2. Stalmans I, Callanan DG, Dirks MS, Moster MR, Robin AL, Van Calster J, Scheib SA, Dickerson JE Jr, Landry TA, Bergamini MV. Treatment of steroid-induced elevated intraocular pressure with anecortave acetate: a randomized clinical trial. J Ocul Pharmacol Ther. 2012 Dec;28(6):559-6doi: 10.1089/jop.2012.006Epub 2012 Aug PubMed PMID: 22860637; PubMed Central PMCID: PMC3505827. 3. Missel P, Chastain J, Mitra A, Kompella U, Kansara V, Duvvuri S, Amrite A, Cheruvu N. In vitro transport and partitioning of AL-4940, active metabolite of angiostatic agent anecortave acetate, in ocular tissues of the posterior segment. J Ocul Pharmacol Ther. 2010 Apr;26(2):137-46. doi: 10.1089/jop.2009.013PubMed PMID: 20415622; PubMed Central PMCID: PMC3158576. 4. Bajenaru ML, Piña Y, Murray TG, Cebulla CM, Feuer W, Jockovich ME, Marin Castaño ME. Gelatinase expression in retinoblastoma: modulation of LH(BETA)T(AG) retinal tumor development by anecortave acetate. Invest Ophthalmol Vis Sci. 2010 Jun;51(6):2860-doi: 10.1167/iovs.09-4500. Epub 2010 Jan 27. PubMed PMID: 20107171; PubMed Central PMCID: PMC2891454.

Related compound libraries

This product is contained In the following compound libraries：

Drug Repurposing Compound Library Anti-Cardiovascular Disease Compound Library Pediatric Drug Library Bioactive Compound Library Clinical Compound Library Anti-Hypertension Compound Library Bioactive Compounds Library Max NO PAINS Compound Library

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Anecortave Acetate 7753-60-8 Others NSC-15475 Retaane Al 3789 NSC24345 NSC 24345 NSC 15475 NSC-24345 NSC15475 Anecortave inhibitor inhibit

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