GPCR/G Protein Histamine Receptor Acrivastine


Catalog No. T4551   CAS 87848-99-5
Synonyms: BW825C, Semprex, Acrivastin, Semprex, BW825C, Acrivastin

Acrivastine is a short-acting histamine 1 receptor antagonist.

Acrivastine, CAS 87848-99-5
Pack Size Availability Price/USD Quantity
5 mg In stock 44.00
10 mg In stock 53.00
25 mg In stock 118.00
50 mg In stock 182.00
100 mg In stock 260.00
1 mL * 10 mM (in DMSO) In stock 50.00
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Purity 100.00%
Purity 99.85%
Biological Description
Chemical Properties
Storage & Solubility Information
Description Acrivastine is a short-acting histamine 1 receptor antagonist.
In vivo Acrivastine (usually 8mg three times daily) is an effective and well-tolerated antihistamine in the treatment of chronic urticaria and allergic rhinitis. Acrivastine causes less drowsiness than clemastine, the incidence of adverse effects being indistinguishable from that with placebo or terfenadine. In the treatment of dermatoses in which histamine has a pathogenetic role, the efficacy of acrivastine is superior to that of placebo and similar to that of usual dosages of clemastine, hydroxyzine, chlorpheniramine, cyproheptadine or terfenadine [1]. Both 4 mg and 8 mg acrivastine alleviate the symptoms of seasonal allergic rhinitis with significant improvements in the symptom scores for sneezing, running nose and the calculated overall score. In addition, 8 mg acrivastine reduces the symptom scores for watery eyes and itchy throat. Acrivastine is both well tolerated and effective in the treatment of seasonal allergic rhinitis [2].
Synonyms BW825C , Semprex , Acrivastin , Semprex , BW825C , Acrivastin
Purity 100.00%
Molecular Weight 348.44
Formula C22H24N2O2
CAS No. 87848-99-5


0-4℃ for short term (days to weeks), or -20℃ for long term (months).

Solubility Information

DMSO: 10 mg/mL, warmed&ultrasonic

( < 1 mg/ml refers to the product slightly soluble or insoluble )


References and Literature
1. Brogden RN, et al. Acrivastine. A review of its pharmacological properties and therapeutic efficacy in allergic rhinitis, urticaria and related disorders. Drugs. 1991 Jun;41(6):927-40. 2. Gibbs TG, et al. Acrivastine in two doses compared with placebo in a multicentre, parallel group study for the treatment of seasonal allergic rhinitis. Br J Clin Pract. 1989 Jan;43(1):11-4.

Related compound libraries

This product is contained In the following compound libraries:
Approved Drug Library Bioactive Compound Library Inhibitor Library Neuronal Signaling Compound Library Histamine & Melatonin Library FDA-approved Drug Library Immunology/Inflammation Compound Library GPCR Compound Library Drug Repurposing Library Neurotransmitter Receptor Compound Library Target-Focused Phenotypic Screening Library Anti-COVID-19 Compound Library PLpro-Targeted compound library (CADD) Drug-induced Liver Injury (DILI) Compound Library Nonsteroidal Antiinflammatory Compound Library NMPA-Approved Drug Library FDA Approved & Pharmacopeial Drug Library

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