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AZD5305

Name: AZD5305
Brand: TargetMol
SKU: T9165
Price: 115 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T9165Cas No. 2589531-76-8

AZD5305 is a potent, selective and oral active PARP inhibitor.

AZD5305

🥰Excellent

Purity: 99.93%

Catalog No. T9165Cas No. 2589531-76-8

AZD5305 is a potent, selective and oral active PARP inhibitor.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$115	In Stock	In Stock
5 mg	$247	In Stock	In Stock
10 mg	$397	In Stock	In Stock
25 mg	$663	-	In Stock
50 mg	$945	In Stock	In Stock
100 mg	$1,280	-	In Stock
1 mL x 10 mM (in DMSO)	$272	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

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Purity:99.93%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	AZD5305 is a potent, selective and oral active PARP inhibitor.
In vivo	AZD5305 is potent and efficacious in animal xenografts and PDX models.

Chemical Properties

Molecular Weight	406.48
Formula	C₂₂H₂₆N₆O₂
Cas No.	2589531-76-8
Smiles	CCc1cc2ncc(CN3CCN(CC3)c3ccc(nc3)C(=O)NC)cc2[nH]c1=O
Relative Density.	1.246 g/cm3 (Predicted)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 41.67 mg/mL (102.51 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.4601 mL	12.3007 mL	24.6015 mL	123.0073 mL
5 mM	0.4920 mL	2.4601 mL	4.9203 mL	24.6015 mL
10 mM	0.2460 mL	1.2301 mL	2.4601 mL	12.3007 mL
20 mM	0.1230 mL	0.6150 mL	1.2301 mL	6.1504 mL
50 mM	0.0492 mL	0.2460 mL	0.4920 mL	2.4601 mL
100 mM	0.0246 mL	0.1230 mL	0.2460 mL	1.2301 mL

Calculator

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc