1,2,3,6-Tetragalloylglucose
Catalog No. TN1160 CAS
79886-50-3
Synonyms:
1,2,3,6-Tetra-O-galloyl-β-D-glucose, 1,2,3,6-四-O-没食子酰-Β-D-葡萄糖, TeGG
1,2,3,6-Tetragalloylglucose has antioxidative activity, it also shows the most potent anticomplement activity (IC50 = 34 microM). 1,2,3,6-Tetragalloylglucose is also a potent inhibitor of UDP glucuronosyltransferase 1 A1 (UGT1A1, Ki = 1.68 μM).
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1,2,3,6-Tetragalloylglucose, CAS 79886-50-3
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Biological Description
Chemical Properties
Storage
& Solubility Information
Description |
1,2,3,6-Tetragalloylglucose has antioxidative activity, it also shows the most potent anticomplement activity (IC50 = 34 microM). 1,2,3,6-Tetragalloylglucose is also a potent inhibitor of UDP glucuronosyltransferase 1 A1 (UGT1A1, Ki = 1.68 μM). |
Targets&IC50 |
UGT1A1:1.68 μM(Ki), anticomplement activity:34 microM
|
In vitro |
Two phenolics, 1,2,6-trigalloylglucose (1) and 1,2,3,6-Tetragalloylglucose (2), isolated from the stem-bark of Juglans mandshurica were evaluated for their antioxidative activities. The results showed that compounds 1 and 1,2,3,6-Tetragalloylglucose exhibited strong scavenging activities against 1,1'-diphenyl-1-picrylhydrazyl (DPPH), 2,2'-azino-bis-(3-ethylbenzenthiazoline-6-sulphonic) acid (ABTS(*+)), and superoxide radicals (O(2)(*-)), and also had a significant inhibitory effect on lipid peroxidation and low-density lipoprotein (LDL) oxidation[1] |
Synonyms |
1,2,3,6-Tetra-O-galloyl-β-D-glucose, 1,2,3,6-四-O-没食子酰-Β-D-葡萄糖, TeGG
|
Molecular Weight |
788.57
|
Formula |
C34H28O22 |
CAS No. |
79886-50-3 |
Storage
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
Solubility Information
DMSO: 91 mg/mL (115.40 mM)
( < 1 mg/ml refers to the product slightly soluble or insoluble )
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Keywords
1,2,3,6-Tetragalloylglucose
79886-50-3
代谢
LDL
UGT
Inhibitor
TeGG
1,2,3,6Tetragalloylglucose
inhibit
1,2,3,6 Tetragalloylglucose
1,2,3,6-Tetra-O-galloyl-β-D-glucose
inhibitor