β-lactamases — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T4017	Relebactam	MK-7655	Antibacterial
	Relebactam (MK-7655) is a diazabicyclooctane inhibitor with activity against a wide spectrum of β-lactamases.		Antibacterial
T0224	Meropenem	SM 7338	Others , Antibacterial , Antibiotic
	Meropenem (SM 7338) is a carbapenem antibiotic with broad spectrum of activity that is administered intravenously and used for severe bacterial infections due to sensitive agents. Meropenem is a common cause of mild tran...		Others , Antibacterial , Antibiotic
T12004	Meropenem trihydrate	SM 7338 trihydrate	Antibacterial , Antibiotic
	Meropenem trihydrate (SM 7338 trihydrate) with broad-spectrum antibacterial activity,is a carbapenem antibiotic.		Antibacterial , Antibiotic
T6179	Moxalactam sodium salt	Latamoxef sodium,6059 S,Moxalactam Disodium,LY-127935,Antibiotic 6059S,Shiomarin,FestamoxinLy	Antibacterial , Antibiotic
	Moxalactam sodium salt (LY-127935) is an antibiotic compound more effective against Escherichia coli and Pseudomonas aeruginosathan cephalosporins.		Antibacterial , Antibiotic
T12166	Nacubactam	OP0595 free acid	Antibacterial
	Nacubactam (OP0595 free acid) is a potent inhibitor of non-β-lactam-β-lactamase with activity against class A and class C β-lactamases.		Antibacterial
T19709	Nitrocefin		Others
	Nitrocefin is an antibiotic. It being sensitive to hydrolysis by all lactamases produced by gram-positive and gram-negative bacteria.		Others
T4201	Avibactam sodium	AVE-1330A,NXL-104	Antibacterial , Antibiotic
	Avibactam sodium (NXL-104) is a reversible β-lactamase inhibitor (IC50: 8/80/38 nM, for TEM-1/P99/KPC-2 β-lactamases).		Antibacterial , Antibiotic
T4991	Ertapenem sodium	MK-826,L-749345	Antibacterial , Antibiotic
	Ertapenem sodium (MK-826) is a new long-acting 1-β-methyl carbapenem antibiotic with a broad antibacterial spectrum including common aerobic and anaerobic bacteria and organisms with extended-spectrum β-lactamases.		Antibacterial , Antibiotic
T23801	WCK-4234 sodium	WCK-4234,WCK4234,WCK 4234	Antibacterial
	WCK-4234 sodium (WCK 4234) is an inhibitor of β-lactamase can be used in studies targeting MDR infections. WCK-4234 sodium inhibits class A, C, and D β-lactamases and OXA carbapenemases.		Antibacterial
T1262	Tazobactam	Tazobactamum,Tazobactam acid,YTR-830H,CL-298741	Antibacterial , Antibiotic
	Tazobactam (YTR-830H) is an antibacterial penicillin derivative which inhibits the action of bacterial beta-lactamases.		Antibacterial , Antibiotic
T4501	Ceftizoxime	Epocelin	Antibacterial , Antibiotic
	Ceftizoxime (Epocelin) is a cephalosporin-based, potent antibacterial agent which can be administered intravenously or by suppository. It is highly resistant to a broad spectrum of beta-lactamases and is active against a...		Antibacterial , Antibiotic
T1190	Cefmenoxime hydrochloride	Cefmenoxime hemihydrochloride,SCE-1365 hemihydrochloride	Antibacterial , Antibiotic , Antifection
	Cefmenoxime hydrochloride (Cefmenoxime hemihydrochloride) is a cephalosporin antibiotic that is administered intravenously or intramuscularly. It is active against most common gram-positive and gram-negative microorganis...		Antibacterial , Antibiotic , Antifection
T26980	Cephamycin C	A 16886B,A16886B, A-16886B
	Cephamycin C (CepC) is a nontoxic β-lactam antibiotic. CepC stands out from other cephalosporins for its greater resistance to β-lactamases.
T24942	VNRX-5133	VNRX 5133
	VNRX-5133 is an injectable broad-spectrum β-lactamase inhibitor. VNRX-5133 is a novel β-lactamase inhibitor with potent and selective direct inhibitory activity against both serines- and Metallo-β-lactamases.
T68149	Tacapenem
	Tacapenem is a β-lactam class antibacterial. It exhibits broad-spectrum antibacterial activity and it is highly stable to β-lactamases.
T69797	ETX0282
	ETX0282 is an orally available, broad spectrum inhibitor of class A and C β-lactamases. Entasis is developing ETX0282 in combination with cefpodoxime proxetil, an orally available cephalosporin approved for treatment of ...
T61173	Metallo-β-lactamase-IN-5
	Metallo-β-lactamase-IN-5 (compound 5c) is a powerful inhibitor of metallo-β-lactamases (MBLs). Its inhibitory activity against MBLs NDM-1 and VIM-1 has been demonstrated. With an IC50 value of 45 μg/mL, Metallo-β-lactama...
T39758	ARX-1796	ARX-1796,AV-006
	ARX-1796 (AV-006), an Avibactam prodrug, is an orally bioavailable β-lactamase inhibitor. Avibactam has a spectrum of inhibition of class A and C β-lactamases, including ESBLs, AmpC and Klebsiella pneumoniae carbapenemas...
T60694	Metallo-β-lactamase-IN-4
	Metallo-β-lactamase-IN-4 (compound 40) is a potent inhibitor of metallo-β-lactamases (MBL) with IC 50 values of 0.5 μM, 2.1 μM, and 3.3 μM for VIM-1, NDM-1 and IMP-7, respectively [1].
T71669	BLI-489 Hydrate
	BLI-489 hydrate is a penicillin β-lactamase inhibitor that acts on classes A and C and some class D β-lactamases.