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Cat No. | Product Name | Synonyms | Targets |
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T64133L | Laniquidar TFA | Laniquidar TFA(197509-46-9 Free base),R101933 | P-gp |
Laniquidar TFA (R101933) is a novel orally available non-competitive P-glycoprotein (P-gp) inhibitor with an IC50 value of 0.51 μM.Laniquidar has limited bioavailability and can be used to modulate the multidrug resistan... | |||
T8426 | Encequidar | HM30181,HM30181A | P-gp |
Encequidar (HM30181A) is a potent and selective P-glycoprotein inhibitor. | |||
T11071 | Dofequidar fumarate | MS-209 | P-gp |
Dofequidar fumarate (MS-209)(MS-209 fumarate), a quinoline-based compound administered orally, is known for counteracting multidrug resistance (MDR) through the inhibition of ABCB1/P-glycoprotein (P-gp) and ABCC1/MDR-ass... | |||
T11578L | Encequidar mesylate | HM30181 mesylate,HM30181A mesylate | P-gp |
Encequidar mesylate (HM30181A mesylate) is a competitive P-glycoprotein inhibitor. | |||
T6018 | Zosuquidar trihydrochloride | Zosuquidar (LY335979) 3HCl,RS 33295-198 trihydrochloride,RS 33295-198 (D06387) 3HCl,Zosuquidar 3HCl,LY-335979 trihydrochloride | P-gp |
Zosuquidar trihydrochloride (LY-335979 trihydrochloride) is a potent modulator of P-glycoprotein-mediated multi-drug resistance with Ki of 60 nM. Phase 3. | |||
T6287 | Tariquidar | XR9576 | P-gp |
Tariquidar (XR9576)(Kd=5.1 nM) is a specific and effective non-competitive inhibitor of P-glycoprotein. It can reverse drug resistance in MDR cell Lines. | |||
T6287L | Tariquidar dimesylate | D 06008,XR9576,D06008,XR 9576,Tariquidar dimesilate,XR-9576 | |
Tariquidar is a P-glycoprotein inhibitor undergoing research as an adjuvant against multidrug resistance in cancer. Tariquidar non-competitively binds to the p-glycoprotein transporter, thereby inhibiting transmembrane t... | |||
T68568 | Encequidar, HCl | ||
Encequidar, also known as HM-30181, is an oral P-glycoprotein (P-gp) inhibitor developed to enhance the oral bioavailability of P-gp substrate drugs. Encequidar showed the highest potency (IC(50)=0.63nM) among several MD... | |||
T64133 | Laniquidar | ||
Laniquidar (R101933) is a third generation non-competitive inhibitor of P-glycoprotein (P-gp) (IC50: 0.51 μM) with limited oral bioavailability. It can also be used to modulate multidrug resistance transporters. | |||
T72186 | Tariquidar dihydrochloride | XR9576 dihydrochloride | |
Tariquidar dihydrochloride, also known as XR9576 dihydrochloride, is a potent, specific P-glycoprotein (P-gp) inhibitor exhibiting high affinity (Kd = 5.1 nM). | |||
T6018L | Zosuquidar | ||
Zosuquidar (LY335979) is an inhibitor of P-glycoprotein with a Ki value of 59 nM. Zosuquidar has anti-tumor activities, and can be used in acute myelogenous leukemia (AML) research. | |||
TQ0043 | Dofequidar | MS-209 | P-gp |
Dofequidar (MS-209) is a quinoline compound that can reverse P-glycoprotein (P-gp)-mediated MDR. | |||
T13087 | Tariquidar methanesulfonate, hydrate | XR9576 methanesulfonate, hydrate | Others |
Tariquidar methanesulfonate, hydrate is a potent and specific P-glycoprotein (P-gp) inhibitor(Kd of 5.1 nM). | |||
T35064 | Viquidacin | NXL101,NXL-101,NXL 101 | |
Viquidacin ( NXL-101) is an oral/intravenous antibiotic that targets Gram-positive bacteria such as MRSA. In 2008, Novexel announced it had discontinued the development of Viquidacin (NXL 101). |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T2S0605 | Liquidambaric lactone | HIV Protease | |
Liquidambaric lactone is a compound isolated from Euonymus grandiflorus Wall.Liquidambaric lactone may have inhibitory HIV-1 reverse transcriptase activity. |
Cat No. | Product Name | Species | Expression System |
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TMPJ-00787 | GUSB Protein, E. coli, Recombinant (His) | E. coli | E. coli |
Beta-D-glucuronidase from E.coli is a highly specific enzyme in hydrolyzing glucuronides. Beta-D-glucuronidase (GLUase) activity can be measured as the rate of production of fluorescent methylumbelliferone (MU), resulti... |