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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T1476 | Pramipexole | SND 919 | Dopamine Receptor |
Pramipexole (SND 919) is a selective dopamine receptor agonist used in the therapy of Parkinson disease. Pramipexole therapy is associated with a low rate of transient serum enzyme elevations during treatment but has not... | |||
T6951 | Pramipexole dihydrochloride hydrate | Pramipexole 2HCl Monohydrate,Mirapex | Dopamine Receptor |
Pramipexole dihydrochloride hydrate (Mirapex) is the hydrochloride salt of pramipexole, a benzothiazole derivative. As a nonergot dopamine agonist, pramipexole binds to D2 and D3 dopamine receptors in the striatum and su... | |||
T6647 | Rotigotine- | Neupro,N-0923,N-0437,SPM 962 | Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor |
Rotigotine (N-0923) is a non-ergot dopamine receptor agonist used in the therapy of Parkinson disease and restless leg syndrome. Administered as a once-daily transdermal patch, Rotigotine has not been associated with ser... | |||
T6552 | Istradefylline | KW-6002 | Adenosine Receptor |
Istradefylline (KW-6002)(Ki of 2.2 nM) is a selective adenosine A2A receptor (A2AR) antagonist, which is under development in Phase 3 trails. It has been used in trials studying the treatment and basic science of Drug Ab... | |||
T6651L | Safinamide | EMD1195686,FCE26743,FCE 26743,EMD-1195686,EMD 1195686,FCE-26743 | MAO |
Safinamide (FCE-26743) is a reversible and selective monoamine oxidase B (IC50 0.098μM) inhibitor, reducing the degradation of dopamine, and a glutamate release inhibitor (IC50 8μM). It also inhibits dopamine reuptake. S... | |||
T29184 | YM44778 | YM-44778,YM 44778 | |
YM44778 is a NK1-receptor antagonist for treating restless legs syndrome. |