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Search Results for " restenosis "

8

Compounds

Cat No. Product Name Synonyms Targets
T6033 Zotarolimus ABT-578,A 179578 mTOR
Zotarolimus (ABT-578), an analogue of rapamycin, inhibits FKBP-12 (IC50= 2.8 nM).
T8687 Diaminohydroxypropanetetraacetic acid Others
Diaminohydroxypropanetetraacetic acid has been investigated for the treatment of Vascular Disease, Coronary Disease, Myocardial Ischemia, Coronary Restenosis, and Coronary Artery Disease, among others
T6S0655 Corynoxeine ERK
1. Corynoxeine is a potent ERK1/2 inhibitor of key PDGF-BB-induced VSMC proliferation and may be useful in the prevention and treatment of vascular diseases and restenosis after angioplasty.
T24873 TGX-115 TGX 115 PI3K
TGX-115 is a cell-permeable and potent inhibitor of the PI 3-K isoform p110β/p110δ (IC50 values of 0.13 μM for p110β and 0.63 μM for p110δ), an enzyme that regulates platelet adhesion and inhibits phosphoinositide (PI) 3...
T15696 NEP-IN-2 Others
NEP-IN-2 is an inhibitor of neutral endopeptidase. It also is used in the research of proliferation in atherosclerosis, restenosis.
T64285 Protease-Activated Receptor-1 antagonist 2
Protease-Activated Receptor-1 antagonist 2 is a selective, orally active protease-activated receptor-1 (PAR-1) antagonist (IC50: 7 nM). It has shown good pharmacokinetic properties and can be used for studies related to ...
T68639 Ciprostene (free base)
Ciprostene (free base) is a synthetic, chemically stable analog of prostacyclin (PGI2). In animal models, administration of ciprostene resulted in dose-dependent hypotension, tachycardia, and inhibition of ex vivo ADP-in...
T74266 Protease-Activated Receptor-1 antagonist 2
Protease-Activated Receptor-1 Antagonist 2 is an orally active antagonist of protease-activated receptor-1 (PAR-1), demonstrating significant potency with an IC 50 of 7 nM. It exhibits favorable pharmacokinetic character...
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