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TGX-115

Catalog No. T24873 CAS 351071-62-0

Synonyms: TGX 115

TGX-115 is a cell-permeable and potent inhibitor of the PI 3-K isoform p110β/p110δ (IC50 values of 0.13 μM for p110β and 0.63 μM for p110δ), an enzyme that regulates platelet adhesion and inhibits phosphoinositide (PI) 3-kinase, and can be used to treat coronary artery occlusion, stroke, acute coronary artery It can be used to treat cardiovascular diseases such as coronary occlusion, stroke, acute coronary syndrome, acute myocardial infarction, restenosis, atherosclerosis and unstable angina.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

TGX-115, CAS 351071-62-0

Pack Size	Availability	Price/USD
1 mg	In stock	$ 350.00
5 mg	In stock	$ 828.00
10 mg	In stock	$ 1,130.00
25 mg	In stock	$ 1,590.00
50 mg	In stock	$ 1,980.00
100 mg	In stock	$ 2,500.00
500 mg	In stock	$ 4,900.00
1 mL * 10 mM (in DMSO)	In stock	$ 683.00

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Purity: 99.31%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	TGX 115
Molecular Weight	336.38
Formula	C20H20N2O3
CAS No.	351071-62-0

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 2 years

Solubility Information

DMSO: 22.5 mg/mL (66.89 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Knight ZA, et al. Isoform-specific phosphoinositide 3-kinase inhibitors from an arylmorpholine scaffold. Bioorg Med Chem. 2004 ; 12(17):4749-4759.

Related compound libraries

This product is contained In the following compound libraries：

Bioactive Compounds Library Max Metabolism Compound Library Anti-Cancer Compound Library Anti-Obesity Compound Library Antioxidant Compound Library Bioactive Compound Library Anti-Cancer Metabolism Compound Library

Related Products

Related compounds with same targets

Sennidin A Sennidin B AZD3458 PI3kδ inhibitor 1 Isoangustone A PI3K/mTOR Inhibitor-1 PI3Kdelta inhibitor 1 α-Solanine

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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The answer of 19.713 mg appears in the Mass box

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

TGX-115 351071-62-0 PI3K/Akt/mTOR signaling PI3K TGX115 TGX 115 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.