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Search Result

Search Results for " p38δ "

Targets

p38 MAPK

13

Compounds

2

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T11943 MAPK13-IN-1 p38 MAPK
MAPK13-IN-1 is a potent MAPK13 (p38δ) inhibitor (IC50: 620 nM).
T16812 RWJ-67657 JNJ 3026582 p38 MAPK
RWJ-67657 (JNJ 3026582) is an orally active and selective p38α and p38β MAPK inhibitor (IC50s: 1 and 11 μM, respectively). RWJ-67657 shows no activity at p38γ and p38δ and shows a cardioprotective effect.
T6927 Pamapimod R1503,Ro4402257 p38 MAPK , Autophagy
Pamapimod (R1503) (R-1503, Ro4402257) is a novel, selective inhibitor of p38 mitogen-activated protein kinase. It inhibits p38α and p38β enzymatic activity with IC50 values of 0.014±0.002 and 0.48± 0.04 microM, respectiv...
T18681 SJFα Others
SJFα is a 13-atom linker PROTAC. SJFα degrades p38α with a DC50 of 7.16 nM, but is far less effective at degrading p38δ (DC50=299 nM) and does not degrade the other p38 isoforms (β and γ) at concentrations up to 2.5 μM[...
T36011 P38 MAP Kinase Inhibitor IV p38 MAPK Inhibitor IV
p38 MAPK inhibitor IV is an ATP-competitive inhibitor of p38 MAP kinases with IC50 values of 0.13, 0.55, 5.47, and 8.63 μM for p38α, p38β, p38x, and p38δ, respectively, in vitro.[1] It also inhibits LPS-induced TNF-α an...
T10298 AMG-548 hydrochloride (864249-60-5 free base) AMG-548 hydrochloride p38 MAPK
AMG-548 hydrochloride is an orally active and selective p38α inhibitor (Ki: 0.5 nM) and shows slightly selective over p38β (Ki: 36 nM) and >1000 fold selective against p38γ/p38δ. It is also extremely potent in the inhibi...
T10298L AMG-548 p38 MAPK
AMG-548 is an orally active and selective p38α inhibitor (Ki=0.5 nM), shows slightly selective over p38β (Ki=36 nM) and >1000 fold selective against p38γ and p38δ and is also extremely potent in the inhibition of whole b...
T10298L2 AMG-548 dihydrochloride (864249-60-5 free base) AMG-548 dihydrochloride p38 MAPK
AMG-548 dihydrochloride is an orally active and selective p38α inhibitor (Ki: 0.5 nM) and shows slightly selective over p38β (Ki: 36 nM) and >1000 fold selective against p38γ/p38δ. It is also extremely potent in the inhi...
T36260 NR 7h
Potent and selective p38α and p38β degrader (DC50 < 50 nM). Displays no significant degradation of p38γ, p38δ, JNK1/2 or ERK1/2. Inhibits phosphorylation of MK2 in UV-treated cancer cells and LPS-stimulated bone marrow-d...
T18682 SJFδ Others
SJFδ is a 10-atom linker PROTAC. SJFδ degrades p38δ with a DC50 of 46.17 nM, but does not degrade p38α, p38β, or p38γ[1].
T70638 P38-α MAPK-IN-5
P38-α MAPK-IN-5 is a potent inhibitor of p38α, demonstrating inhibitory concentrations (IC50) of 0.1 nM for p38α, 0.2 nM for p38β, 944 nM for p38γ, and 4100 nM for p38δ. It exhibits anti-inflammatory properties and holds...
T63762 AMG-548 dihydrochloride
AMG-548 dihydrochloride is a selective, orally active p38α inhibitor with a Ki value of 0.5 nM, a slight selectivity for p38β (Ki=36 nM) and >1000-fold selectivity for p38γ and p38δ. AMG-548 dihydrochloride exhibits inhi...
T63371 AMG-548 hydrochloride
AMG-548 hydrochloride is a selective, orally active p38α inhibitor with a Ki value of 0.5 nM, a slight selectivity for p38β (Ki=36 nM) and a 1000-fold selectivity for p38γ and p38δ. AMG 548 hydrochloride also effectively...

Recombinant Proteins

Species：
Human (2)
Expression System：
Baculovirus Insect Cells (2)
Tag：
GST (2)
Cat No. Product Name Species Expression System
TMPY-04551 P38 delta/MAPK13 Protein, Human, Recombinant (GST) Human Baculovirus Insect Cells
p38 delta/MAPK13 Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag. The predicted molecular weight is 68.4 kDa and the accession number is O15264.
TMPY-04531 P38 delta/MAPK13 Protein, Human, Recombinant (GST), Activated in vitro Human Baculovirus Insect Cells
p38 delta/MAPK13 Protein, Human, Recombinant (GST), Activated in vitro is expressed in Baculovirus insect cells with GST tag. The predicted molecular weight is 68.4 kDa and the accession number is O15264.
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