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MAPK13-IN-1

Catalog No. T11943 CAS 229002-10-2

MAPK13-IN-1 is a potent MAPK13 (p38δ) inhibitor (IC50: 620 nM).

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MAPK13-IN-1, CAS 229002-10-2

Pack Size	Availability	Price/USD
1 mg	In stock	$ 118.00
5 mg	In stock	$ 291.00
10 mg	In stock	$ 432.00
25 mg	In stock	$ 715.00
50 mg	In stock	$ 987.00
100 mg	In stock	$ 1,360.00
1 mL * 10 mM (in DMSO)	In stock	$ 293.00

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Purity: 99.55%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	MAPK13-IN-1 is a potent MAPK13 (p38δ) inhibitor (IC50: 620 nM).
Targets&IC50	MAPK13 p38δ:620 nM

Molecular Weight	365.43
Formula	C20H23N5O2
CAS No.	229002-10-2

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 73.09 mg/mL (200 mM)

References and Literature

1. Yurtsever Z, et al. First comprehensive structural and biophysical analysis of MAPK13 inhibitors targeting DFG-in and DFG-out binding modes. Biochim Biophys Acta. 2016 Nov;1860(11 Pt A):2335-2344. 2. Bouhaddou M, et al. The Global Phosphorylation Landscape of SARS-CoV-2 Infection. Cell. 2020 Aug 6;182(3):685-71e19.

Related compound libraries

This product is contained In the following compound libraries：

Inhibitor Library Kinase Inhibitor Library Covalent Inhibitor Library Bioactive Compound Library Bioactive Compounds Library Max

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

MAPK13-IN-1 229002-10-2 MAPK p38 MAPK MAPK13 IN 1 MAPK-13-IN-1 MAPK13IN1 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.