p-met — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TP1369L	[Sar9,Met(O2)11]-Substance P acetate	[Sar9,Met(O2)11]-Substance P acetate(110880-55-2 free base)	Neurokinin receptor
	[Sar9,Met(O2)11]-Substance P acetate is a tachykinin NK1 receptor selective agonist. [Sar9,Met(O2)11]-Substance P acetate is a selective tachykinin NK1 receptor agonist.[Sar9,Met(O2)11]-Substance P acetate and septide (1...		Neurokinin receptor
T7828	[Sar9,Met(O2)11]-Substance P	Bhsar-sp,NA	Neurokinin receptor
	[Sar9,Met(O2)11]-Substance P (NA) is an agonist of NK1 receptor.		Neurokinin receptor
TP1369	[Sar9,Met(O2)11]-Substance P TFA(110880-55-2,free)	[Sar9,Met(O2)11]-Substance P TFA
	[Sar9,Met(O2)11]-Substance P TFA is a selective tachykinin NK1 receptor agonist.[Sar9,Met(O2)11]-Substance P and septide (10-100 pmol per rat, i.c.v.) are equipotent in increasing mean arterial blood pressure (MAP) and h...
T9052	XL092	CL-092,JUN04542	VEGFR , c-Met/HGFR , TAM Receptor
	XL092 (JUN04542) is an Axl Mer cMet KDR inhibitor for the treatment of Axl and Mer receptor tyrosine kinase- dependent disorders.		VEGFR , c-Met/HGFR , TAM Receptor
T75769	[Sar9,Met(O2)11]-Substance P TFA
	[Sar9,Met(O2)11]-Substance P TFA is a tachykinin NK 1 receptor selective agonist.
T25098	Antiflammin P2	Hdmnkvldl,Antiflamin 2,His-asp-met-asn-lys-val-leu-asp-leu
	Antiflammin P2 is a nonapeptide fragment of lipocortin I which has no phospholipase A2 inhibitory and anti-inflammatory activity.
TQ0210	Savolitinib	AZD-6094,Volitinib,HMPL-504	c-Met/HGFR
	Savolitinib (Volitinib) (AZD-6094) is an effective, selective, and orally bioavailable c-Met inhibitor (IC50s: 5 nM/3 nM for c-Met/p-Met).		c-Met/HGFR
T77575	P-gb-IN-1		P-gp
	P-gb-IN-1 is a potent P-glycoprotein (P-gp) inhibitor that exhibits reverse activity by inhibiting P-gp outflow. P-gb-IN-1 has been shown to inhibit P-gp by hydrogen bonding with residues Asn 721 and Met 986. P-gb-IN-1 s...		P-gp
TP1862L	[Sar9] Substance P acetate(77128-75-7 free base)		Neurokinin receptor
	[Sar9]-Substance P acetate is one of NK-1 receptor agonist. The action of SP on progesterone metabolism was mimicked by the rNK1-specific agonist [Sar-9,Met(O2)11]-SP.		Neurokinin receptor
T76452	Gly-Leu-Met-NH2
	Gly-Leu-Met-NH2 is a C-terminal tripeptide of Substance P ( Substance P ). Substance P is a neuropeptide [1] .
T15384	Glesatinib	MGCD265	c-Met/HGFR
	Glesatinib is an orally active and potent dual inhibitor of MET/SMO. Glesatinib is also a tyrosine kinase inhibitor. It antagonizes P-glycoprotein mediated multidrug resistance (MDR) in NSCLC.		c-Met/HGFR
T76449	Substance P (alligator)
	Substance P (alligator), a neuropeptide derived from alligator, possesses a primary structure delineated as Arg-Pro-Arg-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2 [1].
T15383	Glesatinib hydrochloride	MGCD265 hydrochloride	c-Met/HGFR
	Glesatinib hydrochloride is an orally active and potent dual inhibitor of MET/SMO. Glesatinib hydrochloride is also a tyrosine kinase inhibitor. It antagonizes P-glycoprotein mediated multidrug resistance (MDR) in NSCLC.		c-Met/HGFR
T70456	Nolpitantium Free Base
	Nolpitantium Free Base is a highly selective nonpeptide antagonist of neurokinin-1 (NK1) receptor. Nolpitantium potently, selectively and competitively inhibited substance P binding to NK1 receptors from various animal s...
TP1862	[Sar9] Substance P
	[Sar9]-Substance P is one of NK-1 receptor agonist. The action of SP on progesterone metabolism was mimicked by the rNK1-specific agonist [Sar-9,Met(O2)11]-SP.
T29186	YM49598	YM-49598,YM 49598
	YM49598 is a tachykinin receptor antagonist. YM49598 exhibited high binding affinities at NK(1) (pK(i) = 9.09 +/- 0.02) and NK(2) (pK(i) = 9.94 +/- 0.03) receptors, respectively. YM49598 was almost inactive but produced ...