nonnucleoside — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T9223	RO-0335		Reverse Transcriptase
	RO-0335 is a potent diphenylether nonnucleoside reverse transcriptase inhibitor. RO-0335 inhibits Wt HIV-1 (IC50 = 1.1 nM) and retained activity (IC50< 100 nM) against 92% of a large number of NNRTI-resistant clinical is...		Reverse Transcriptase
TQ0122L	VCH-916 free acid(1200133-34-1 free base)		HCV Protease
	VCH-916 is a novel nonnucleoside HCV NS5B polymerase inhibitor.		HCV Protease
T27260	Emivirine	MKC442,MKC-442,MKC 442,DRG-0302,DRG 0302,DRG0302	HIV Protease
	Emivirine (MKC-442) is a potent and selective nonnucleoside reverse transcriptase inhibitor of human immunodeficiency virus type 1.		HIV Protease
T8800	NSAH	2-hydroxy-N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]benzohydrazide	DNA/RNA Synthesis
	NSAH (2-hydroxy-N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]benzohydrazide) is a nonnucleoside inhibitor of human ribonucleotide reductase (hRR).with cell-free IC50 of 32 μM and cell-based IC50 of ~250 nM, respectively...		DNA/RNA Synthesis
T12715	Reverse transcriptase-IN-1		HIV Protease
	Reverse transcriptase-IN-1 is a diarylbenzopyrimidine (DABP) analogue and a potent inhibitor of HIV-1 nonnucleoside reverse transcriptase with an IC50of 13.7 nM.		HIV Protease
T30185	AT 61	AT61,AT-61
	AT-61 is a nonnucleoside analogue inhibitor of hepatitis B virus (HBV) replication.
TQ0122	VCH-916		HCV Protease
	VCH-916 is a new nonnucleoside inhibitor of HCV NS5B polymerase.		HCV Protease
T31085	CP-94707	UNII-YGC6408B5O
	CP-94707 is a new inhibitor of nonnucleoside reverse transcriptase (NNRTI).
T25363	Efavirenz, (R)-	L 743725,L-743725,L743725
	Efavirenz, (R)- is an antiviral agent and a nonnucleoside HIV-1 reverse transcriptase inhibitor.
T26442	A 75925	A-75925,A75925
	A 75925, a nonnucleoside reverse transcriptase inhibitors (NNRTI), works to inhibit HIV-1 replication.
T27442	GSK 224876	GSK-224876,GSK224876
	GSK 224876 is a novel next-generation nonnucleoside reverse transcriptase inhibitor (NNRTI). It has activity against efavirenz-resistant strains in the treatment of treatment-naive HIV-1-infected subjects.
T14086	ABT-072		Others
	ABT-072 is a nonnucleoside NS5B polymerase inhibitor and a candidate drug evaluated for treatment of hepatitis C virus.		Others
T24794	SJ-3366	SJ 3366
	SJ3366 is a unique and highly potent nonnucleoside reverse transcriptase human immunodeficiency virus type 1 and HIV-2 inhibitor.
T16081	MIV-150	PC 815	Others
	MIV-150 is a nonnucleoside inhibitor of reverse transcriptase (NNRT). MIV-150 also blocking HIV-1 and HIV-2 infections (EC50<1 nM against HIV-1/HIV-2MN).		Others
T70212	U 95133
	U 95133 is a potent, broad-spectrum nonnucleoside reverse transcriptase inhibitor of drug-resistant isolates of human immunodeficiency virus type 1.
T72283	(+)-Dihydrocalanolide A	NSC 678323,DHCal A ; NSC 678323,DHCal A
	(+)-Dihydrocalanolide A (DHCal A; NSC 678323), an orally active nonnucleoside inhibitor of reverse transcriptase, is utilized in research related to HIV infection.
T78167	PYR01
	PYR01 is a potent nonnucleoside reverse transcriptase inhibitor of HIV-1 and concurrently acts as a targeted activator to eliminate cells expressing HIV-1 [1].