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RO-0335

RO-0335
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Purity:98.9%
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RO-0335

Catalog No. T9223Cas No. 867365-76-2
RO-0335 is a potent diphenylether nonnucleoside reverse transcriptase inhibitor. RO-0335 inhibits Wt HIV-1 (IC50 = 1.1 nM) and retained activity (IC50< 100 nM) against 92% of a large number of NNRTI-resistant clinical isolates.
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Pack SizePrice/USDAvailabilityQuantity
1 mg$51In Stock
5 mg$122In Stock
10 mg$198In Stock
25 mg$455In Stock
50 mg$672In Stock
100 mg$956In Stock
500 mg$1,920In Stock
1 mL x 10 mM (in DMSO)$133In Stock
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Product Introduction

Bioactivity
Description
RO-0335 is a potent diphenylether nonnucleoside reverse transcriptase inhibitor. RO-0335 inhibits Wt HIV-1 (IC50 = 1.1 nM) and retained activity (IC50< 100 nM) against 92% of a large number of NNRTI-resistant clinical isolates.
Chemical Properties
Molecular Weight573.22
FormulaC21H13BrCl2FN3O4S
Cas No.867365-76-2
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 200 mg/mL(348.91 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.7445 mL8.7227 mL17.4453 mL87.2265 mL
5 mM0.3489 mL1.7445 mL3.4891 mL17.4453 mL
10 mM0.1745 mL0.8723 mL1.7445 mL8.7227 mL
20 mM0.0872 mL0.4361 mL0.8723 mL4.3613 mL
50 mM0.0349 mL0.1745 mL0.3489 mL1.7445 mL
100 mM0.0174 mL0.0872 mL0.1745 mL0.8723 mL

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