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Search Results for " mglu7 "

9

Compounds

Cat No. Product Name Synonyms Targets
T21995 XAP044 GluR
XAP044 is a mGlu7-selective antagonist which inhibits lateral amygdala long term potentiation (LTP) in brain slices from wild type mice with a half-maximal blockade at 88 nm[1].
T13321 VU6005649 GluR
VU6005649 is an agonist of CNS penetrant mGlu7/8 receptor (EC50s: 0.65 μM and 2.6 μM for mGlu7 receptor and mGlu8 receptor, respectively).
T13323 VU6012962 GluR
VU6012962 is an orally bioavailable negative allosteric modulator of CNS-penetrant metabotropic glutamate receptor 7(mGlu7; IC50: 347 nM).
T6726 VU0361737 ML-128,VU 0361737 GluR
VU0361737 (ML-128) is a specific positive allosteric modulator (PAM) of mGlu4 receptor.The EC50 of VU 0361737 is 240 nM for the human receptors. The EC50 of VU 0361737 is110 nM for rat receptors.It exhibits weak activity...
T15692 L-AP4 L-APB,L-AP 4 GluR
L-APB is an effective and specific agonist for the group III mGluRs (EC50s: 0.13, 0.29, 1.0, 249 μM for mGlu4, mGlu8, mGlu6, and mGlu7 receptors, respectively).
T23008 MMPIP MMPIP hydrochloride Others
allosteric mGlu7-selective receptor antagonist
T35082 VU6010608 VU-6010608,VU 6010608
VU6010608 is an effective mGlu7 NAM with excellent CNS permeability and is powerful in electrophysiological studies in blocking long-term enhancement of high-frequency stimuli.
T21935 AMN082 AMN 082 dihydrochloride GluR
AMN082 (AMN 082 dihydrochloride) is a selective metabotropic glutamate mGlu7 receptor agonist reported to exhibit antidepressant activity.
T37127 L-AP4 monohydrate L-AP4 monohydrate
L-AP4 (L-APB) monohydrate is a potent and specific agonist for the group III mGluRs, with EC50s of 0.13, 0.29, 1.0, 249 μM for mGlu4, mGlu8, mGlu6 and mGlu7 receptors, respectively[1][2]. L-AP4 (5-30 μg, intrathecal inhe...
TargetMol