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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T22106 | MLS-573151 | CDK , Ras | |
MLS-573151 is a selective inhibitor of GTPase Cdc42(EC50 of 2 μM). It is inactive against other GTPases family members, such as Rab2, Rab7, H-Ras, Rac1, Rac 2 and RhoA wild-type. MLS-573151 acts by blocking the binding... | |||
T81135 | Sodium caseinates | ||
Sodium caseinate, the predominant milk protein salt of casein, promotes the proliferation and activation of granulocytes and elevates serum concentrations of cytokines GM-CSF and G-CSF, thereby inducing murine granulopoi... | |||
TP1597L | Secretoneurin, rat acetate | Secretoneurin, rat acetate(149146-12-3 Free base) | Others |
Secretoneurin, rat acetate is a 33-amino acid polypeptide generated by proteolytic processing of secretogranin II (SgII). Secretoneurin, rat acetate induces dopamine release in the rat striatum in vivo and in vitro, and ... | |||
T27408 | Gea 3162 | Gea3162,Gea-3162 | |
Gea 3162 is a potent inhibitor of ADP-induced platelet aggregation in platelet rich plasma (PRP). GEA 3162 stimulates cGMP production in granulocytes, platelets, and polymorphonuclear leukocytes. | |||
TN6057 | 1-Methyl-2-[(Z)-6-undecenyl]-4(1H)-quinolone | (Z)-1-Methyl-2-(undec-6-enyl)quinolin-4(1H)-one | |
(Z)-1-Methyl-2-(undec-6-enyl)quinolin-4(1H)-one shows strong inhibitory activity on leukotriene biosynthesis in human polymorphonuclear granulocytes, and it is very effective against mycobacteria. | |||
TN2552 | 1-Methyl-2-nonylquinolin-4(1H)-one | Others | |
1-Methyl-2-nonylquinolin-4(1H)-one has anti-inflammatory activity, it exhibits inhibitory activity on leukotriene biosynthesis in a bioassay using human polymorphonuclear granulocytes, with IC50 values of 12.1 microM. | |||
T39009 | CAP18 (rabbit) | CAP18 (rabbit) | |
CAP18 (rabbit) is a 37 amino acid antimicrobial peptide derived from rabbit granulocytes. It exhibits extensive antimicrobial activity against both Gram-positive (IC50, 130-200 nM) and Gram-negative (IC50, 20-100 nM) bac... | |||
T79597 | LUF7690 | ||
LUF7690 (Compound 9), a clickable and covalent affinity-based probe (AfBP) for the human A3 adenosine receptor (hA3AR), facilitates the detection and characterization of hA3AR in various granulocytes and other cell types... | |||
T35541 | Lipoxygenin | ||
Lipoxygenin is an inhibitor of 5-lipoxygenase (5-LO) with an IC50value of 5 μM for inhibition of 5-LO product synthesis in isolated human granulocytes stimulated with the cation ionophore A23187 .1It inhibits hedgehog-de... | |||
T38309 | LL-37 amide (trifluoroacetate salt) | ||
LL-37 is a cationic and α-helical antimicrobial peptide expressed in human bone marrow, testis, granulocytes, and gingival epithelium and is upregulated in psoriatic lesions. It inhibits growth of Gram-positive E. coli D... | |||
T14210 | Amelubant | BIIL 284 | LTR |
Amelubant (BIIL 284) is a prodrug of active metabolites BIIL 260 and BIIL 315. Anti-inflammatory activity[1]. Amelubant (BIIL 284) is a potent, oral and long acting LTB4 receptor antagonist, negligibly binds to LTB4 rece... |