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Search Results for " galectin-1 "

12

Compounds

Cat No. Product Name Synonyms Targets
TQ0265 Indolelactic acid Endogenous Metabolite
Indolelactic acid is a metabolite of tryptophan in Azotobacter vinelandii cultures.
T79380 Galectin-3/galectin-8-IN-1 Galectin
Galectin-3/galectin-8-IN-1 (Compound 53) serves as a dual inhibitor of the Galectin-3 and galectin-8 C-terminal domains, exhibiting dissociation constants (Kd) of 4.12 μM for Galectin-3 and 6.04 μM for galectin-8. It eff...
T61014 Galectin-8-IN-1
Galectin-8-IN-1 is a selective ligand for the galectin-8 N-terminal domain (galectin-8N) with a Kd value of 48 μM. Galectin-8-IN-1 is 15-fold more selective than galectin-3 and even better than other mammalian galectins.
T62454 Galectin-3-IN-1
Galectin-3-IN-1 (Compound 1) is a potent inhibitor of polyvalent galactose lectin-3 (Gal-3). Galectin-3 is involved in many metabolic processes associated with cancer.
T82605 DB21, Galectin-1 Antagonist Galectin
DB21, Galectin-1 Antagonist, is a peptidomimetic conjugated with dibenzofuran, serving as an allosteric inhibitor of galectin-1 (GAL1) interactions with glycans on cell surfaces. This compound enhances the inhibition of ...
T16413 OTX008 Calixarene 0118,PTX008 Galectin
OTX008 (PTX008) is a selective galectin-1 inhibitor.
T38074 Thiodigalactoside Galectin
Thiodigalactoside (TDG), a non-metabolizable disaccharide, serves as an orally active, potent galectin (GAL) inhibitor, exhibiting Kd values of 24 μM and 49 μM for GAL1 and GAL3, respectively. Demonstrating anti-inflamma...
T79381 Galectin-3/galectin-8-IN-2 Galectin
Galectin-3/galectin-8-IN-2 (Compound 57) is a dual inhibitor targeting the C-terminal domains of Galectin-3 and galectin-8, exhibiting dissociation constants (Kd) of 12.8 μM and 2.06 μM, respectively. It effectively inhi...
T69874 LLS30
LLS30 is an allosteric inhibitor of Galectin-1 (Gal-1). LLS30 decreases Gal-1 binding affinity to its binding partners, and potentially overcomes metastatic castration-resistant prostate cancer (mCRPC).
T63485 Apoptosis inducer 8
Apoptosis inducer 8 is a galectin-1 (gal-1)-mediated apoptosis inducer and a PET imaging agent that significantly reduces gal-1 protein levels and can be used in major lung cancer studies worldwide.
T16624 Propargyl-PEG4-CH2CH2-Boc Others
Propargyl-PEG4-CH2CH2-Boc is a PEG- and Alkyl/ether-based non-cleavable ADC linker. Propargyl-PEG5-Boc can used to synthesize ADC inhibitors of Galectin-3[1].
T16620 Propargyl-PEG5-acid Propargyl-PEG4-C2-acid Others
Propargyl-PEG5-acid is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG5-acid can used to synthesize ADC inhibitors of Galectin-3[1].
TargetMol