fola — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T7598	Calcium N5-methyltetrahydrofolate	NSC173328	Others , Antifolate
	Calcium N5-methyltetrahydrofolate (NSC-173328) is the calcium salt of levomefolic acid, which has been proposed for treatment of cardiovascular disease and advanced cancers such as breast and colorectal cancers		Others , Antifolate
T7593	Levomefolate calcium		Antifolate
	Levomefolate calcium is an artificial form of folate. It is a coenzymated form of folic acid and a more bioavailable alternative in dietary supplements.		Antifolate
T26636	Antifolate C2	AGF 154,AGF154,AGF-154	Others
	Antifolate C2 (AGF 154) has antitumor activity with an IC of 0.14 nM measured in a growth inhibition assay of human tumor cells.Antifolate C2 can be used for the study of cancer and autoimmune diseases.		Others
T31224	Piflufolastat	DCFPYL	Epigenetic Reader Domain
	Piflufolastat (DCFPYL) is a PET imaging agent for prostate cancer PSMA. It is a fluorinated prostate-specific membrane antigen (PSMA) preparation. Piflufolastat can be used to prepare piflufolastat F 18 (DCFPyL F-18).		Epigenetic Reader Domain
T21476	Niclofolan	Niclofolano,Bilevon M,Menichlopholan,ME-3625,Niclofolanum
	Niclofolan, a biphenyl anthelmintic compound, is used orally towards the treatment of Fasciola hepatica infection.
T29461	5-Methyltetrahydrofolate triglutamate	5-Me-Thf(glu)3
	5-Methyltetrahydrofolate triglutamate is a form of folic acid.
T7593L	Levomefolate sodium	L 5 MTHF sodium,L-5-MTHF sodium,L5MTHF sodium,
	Levomefolate calcium is a primary biologically active form of folate used at the cellular level for dna reproduction, the cysteine cycle and the regulation of homocysteine
T39103	Pafolacianine	OTL 38
	Pafolacianine (OTL 38) is a near-infrared dye-based fluorescent marker utilized for identifying ovarian cancer lesions during surgeries.
T77270	Cholesterol-PEG-Folate (MW 2000)
	Cholesterol-PEG-Folate (MW 2000), an excipient, facilitates the preparation of folate-conjugated PEG-liposomes [1].
T17984	Folate-PEG3-azide		Others
	Folate-PEG3-azide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system...		Others
T74308	DSPE-PEG-Folate
	DSPE-PEG-Folate (Mw 3350), a derivative of PEG with folic acid content, exhibits targeting capability by binding to folate receptors on cancer cells. It forms micelles/lipid bilayers, facilitating its use in targeted dru...
T82378	Folate-MS432		PROTACs
	Folate-MS432 is a PROTAC that degrades MEKs selectively in cancer cells via folate receptor-dependent pathways.		PROTACs
T40818	Folate-PEG3-amine	Folate-PEG3-amine
	Folate-PEG3-amine is a three-unit polyethylene glycol (PEG) linker, which is cleavable. This linker is specifically employed in the synthesis of antibody-drug conjugates (ADCs).
T25496	Hexaglutamate folate	Pteglu6
	Hexaglutamate folate is a naturally occurring form of folic acid. The bioavailability of dietary folate may be limited by the need for the glutamate moieties to be deconjugated before absorption. Folate deficiency in hum...
T20340	10-Formyldihydrofolate
	10-Formyldihydrofolate is a Methotrexate metabolite. It inhibits thymidylate synthetase and glycinamide ribotide transformylase.
T32705	Levomefolate magnesium	L-Methylfolate magnesium
	Levomefolate magnesium is the magnesium salt of the metabolite of folic acid (Vitamin B9) and it is a predominant active form of folate found in foods and in the blood circulation, accounting for 98% of folates in human ...
T77274	DSPE-PEG-Folate (MW 5000)
	DSPE-PEG-Folate (MW 5000), a derivative of polyethylene glycol (PEG) integrated with folic acid, demonstrates a specific targeting ability by binding to folate receptors on cancer cells. This compound forms micelles/lipi...
T38492	Folate-PEG2-amine	Folate-PEG2-amine
	Folate-PEG2-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system...
T17861	DSPE-PEG46-Folate		Others
	DSPE-PEG46-Folate is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system...		Others
T34942	Triglutamate folate	Pteglu3
	Triglutamate folate is a bioactive chemical.
T32176	Iofolastat I 123	MIP 1072,MIP1072,Iofolastat (123-I),(123)I-MIP-1072,MIP-1072
	Iofolastat I 123 is a diagnostic agent under investigation in clinical trial NCT00992745 (A Phase I Pilot Study in Subjects With Metastatic Prostate Cancer).
T32706	Levomefolate calcium pentahydrate
	Levomefolate calcium pentahydrate is the calcium salt of 5-methyltetrahydrofolic acid, a biologically active form of folic acid that functions, in conjunction with Vitamin B12. Levomefolate is included in formulations of...
T38629	Folate-PEG3-alkyne	Folate-PEG3-alkyne
	Folate-PEG3-alkyne is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome syste...
T26635	Antifolate C1	AGF 94,AGF94,AGF-94
	Antifolate C1 is an inhibitor of de novo purine biosynthesis. Antifolate C1 has selectivity for cellular uptake by high affinity folate receptors and the proton-coupled folate transporter (PCFT) over the reduced folate c...
T29460	5-Methyldihydrofolate
	5-Methyldihydrofolate is the primary biologically active form of folate used for DNA reproduction, the cysteine cycle, and the regulation of homocysteine.
T68232	Epofolate
	Epofolate is folate receptor-targeting antimitotic agent with potential antineoplastic activity. Folate receptor-targeted epothilone BMS753493 contains an epothilone moiety linked to a single folate molecule. Mediated th...

Compounds

Calcium N5-methyltetrahydrofolate

T7598

Synonym: NSC173328

Target: Others, Antifolate

Synonym: AGF 154,AGF154,AGF-154

Target: Epigenetic Reader Domain

Niclofolan

T21476

Synonym: Niclofolano,Bilevon M,Menichlopholan,ME-3625,Niclofolanum

Target:

5-Methyltetrahydrofolate triglutamate

T29461

Synonym: 5-Me-Thf(glu)3

Target:

Levomefolate sodium

T7593L

Synonym: L 5 MTHF sodium,L-5-MTHF sodium,L5MTHF sodium,

Cholesterol-PEG-Folate (MW 2000)

Synonym: Folate-PEG3-amine

Target:

Hexaglutamate folate

T25496

Synonym: Pteglu6

Target:

10-Formyldihydrofolate

T20340

Synonym:

Target:

Levomefolate magnesium

T32705

Synonym: L-Methylfolate magnesium

Target:

DSPE-PEG-Folate (MW 5000)

Synonym: Folate-PEG2-amine

Triglutamate folate

Synonym: MIP 1072,MIP1072,Iofolastat (123-I),(123)I-MIP-1072,MIP-1072

Target:

Levomefolate calcium pentahydrate

Synonym: Folate-PEG3-alkyne

Target:

Antifolate C1

T26635

Synonym: AGF 94,AGF94,AGF-94

Target:

5-Methyldihydrofolate

Cat No.	Product Name	Synonyms	Targets
T31836	Folate sodium	Folic acid, monosodium salt,Folvite sodium
	Folate sodium, as a member of the vitamin B family, can stimulate the hematopoietic system. Folic acid can be used in the treatment and prevention of folate deficiencies and megaloblastic anemia.

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPH-03535	Dihydrofolate reductase Protein, S. aureus, Recombinant (His & Myc)	Staphylococcus aureus	E. coli
	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Dihydrofolate reductase Protein, S. aureus, Recombinant (His & Myc) is expressed...
TMPH-00608	Dihydrofolate reductase Protein, E. coli, Recombinant (His)	E. coli	E. coli
	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
TMPH-03581	Dihydrofolate reductase Protein, S. epidermidis, Recombinant (His)	Staphylococcus epidermidis	E. coli
	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Dihydrofolate reductase Protein, S. epidermidis, Recombinant (His) is expressed ...
TMPH-01224	Dihydrofolate reductase Protein, Human, Recombinant (His)	Human	E. coli
	Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Binds...