2
1
2
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T4657 | WHI-P97 | JAK | |
WHI-P97 is a rationally designed potent inhibitor of JAK-3. IC50 value: Target: JAK3 Treatment of mast cells with WHI-P97 inhibited the translocation of 5-lipoxygenase (5-LO) from the nucleoplasm to the nuclear membrane ... | |||
T4657L | WHI-P97 HCl 211555-05-4(free base) | JAK | |
WHI-P97 HCl is a potent and selective JAK-3 inhibitor. WHI-P97 had an estimated Ki value of 0.09 microM from modeling studies and a measured IC50 value of 2.5 microM in EGFR kinase inhibition assays. WHI-P97 effectively ... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TN4986 | Selinidin | IκB/IKK , p38 MAPK , TNF | |
Selinidin decreases phosphorylation of phospholipase C-gamma1, p38 mitogen-activated protein kinase, and IkappaB-alpha upon FcepsilonRI stimulation. |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-03064 | Fc epsilon RI Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
Fc epsilon RI Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48 kDa and the accession number is P20489. | |||
TMPK-00149 | Fc epsilon RI alpha/FCER1a Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Known susceptibility genes to atopy and asthma have been identified by linkage or associations with clinical phenotypes, including total serum IgE levels. IgE-mediated sensitivity reactions require a high-affinity IgE re... |