extravasation — TargetMol Chemicals

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Search Results for " extravasation "

Compounds

Cat No.	Product Name	Synonyms	Targets
T1092	Zolmitriptan	311C90,BW-311C90	5-HT Receptor
	Zolmitriptan (311C90) selectively binds to and activates serotonin (5-HT) 1B receptors expressed in intracranial arteries and 5-HT 1D receptors located on peripheral trigeminal sensory nerve terminals in the meninges and...		5-HT Receptor
T7340	5'-N-Ethylcarboxamidoadenosine	NECA	Adenosine Receptor
	5'-N-Ethylcarboxamidoadenosine (NECA) is an agonist of Adenosine receptor, increases cerebral extravasation of fluorescein and low molecular weight dextran independent of blood-brain barrier modulation.		Adenosine Receptor
T1638	N-Acetylneuraminic acid	Acide aceneuramique,NeuAc,Lactaminic acid	Others , Influenza Virus , Endogenous Metabolite
	N-Acetylneuraminic acid (Acide aceneuramique) is a nine-carbon sialic acid monosaccharide commonly found in glycoproteins on cell membranes and in glycolipids such as gangliosides in mammalian cells. Studies have shown t...		Others , Influenza Virus , Endogenous Metabolite
T70248	4991W93
	4991W93 is a 5HT(1B/1D) receptor partial agonist, inhibiting electrically induced plasma extravasation, blocking neurogenic plasma protein extravasation, inhibiting release of calcitonin gene-related peptide.
T28431	PNU109291	PNU-109291,PNU 109291
	PNU109291, a potent and selective agonist of the 5-HT1D receptor, effectively mitigates dural plasma extravasation induced by trigeminal ganglion stimulation.
T27059	CP-122288
	CP-122288 is a potent and selective agonist for the 5-HT1B, 5-HT1D and 5-HT1F serotonin receptor subtypes. CP-122288 is potent as an inhibitor of plasma protein extravasation and neurogenic inflammation.
TP1919	Ac2-12
	Annexin/lipocortin 1-mimetic peptide; inhibits leukocyte extravasation. Reduces neutrophil adhesion and emigration, and promotes detachment of neutrophils from activated mesenteric endothelium in mice in vivo.
TP2083	Ac9-25
	N-terminal peptide of Annexin I (AI/Lipocortin I) that inhibits leukocyte extravasation. Acts as a formyl peptide receptor 1 (FPR1) ligand and stimulates neutrophil NADPH oxidase activation.
T83211	Ac2-12 TFA
	Ac2-12 TFA, an annexin/lipocortin 1 (LC1)-mimetic peptide, inhibits neutrophil extravasation and demonstrates antimigratory effects by attenuating the recruitment of neutrophils in experimental models of inflammation [1]...
T68904	GW-833972A free base
	GW833972 is a CB2 Agonist. GW 833972A inhibited capsaicin-induced depolarization of the human and guinea-pig and prostaglandin E(2) (PGE(2)) and hypertonic saline-induced depolarization of the guinea-pig isolated vagus n...
T26781	BF-1	BF1
	BF-1 is a 5-Hydroxytryptamine receptor 2B antagonist. BF-1 was tested as potential migraine prophylactic drug by blocking BW723C86 (5-((thiophen-2-yl)methoxy)-α-methyltryptamine) or meta-chlorophenylpiperazine (mCPP) ind...
T76841	Enlimomab
	Enlimomab (BI-RR 0001), a murine IgG2a monoclonal antibody targeting human ICAM-1, reduces leukocyte adhesion to the vascular endothelium, thus diminishing leukocyte extravasation and inflammatory tissue damage. This com...
TP2104	UFP-803	UFP 803
	Urotensin-II (UT) receptor ligand; behaves as a silent antagonist in most in vitro assays and in vivo, but does retain small residual agonist activity under certain conditions in some assays. Competitively antagonizes U-...