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Search Results for " cortistatin-a "

12

Compounds

Cat No. Product Name Synonyms Targets
T23909 Cortistatin A Cortistatin-A
Cortistatin A is a potent and selective mediator-associated kinase CDK8 and its paralogue CDK19 inhibitor.
T14778 BRD6989 IL Receptor , CDK , Interleukin
BRD6989 is an analog of the natural product cortistatin A (dCA). Which inhibits CDK8 and upregulates IL-10. BRD6989 inhibits the kinase activity of recombinant CDK8 or CDK19 complexes. BRD6989 selectively binds a complex...
TP1188L Cortistatin 14, human, rat acetate Somatostatin
Cortistatin 14, human, rat acetate is a neuropeptide having structural similarity to somatostatin-14 and shows anticonvulsive, neuroprotective effects and remarkable anti-inflammatory properties. Cortistatin 14, human, r...
TP1570L Cortistatin-14 acetate Cortistatin-14 acetate(186901-48-4 Free base) Somatostatin
Cortistatin-14 acetate, a neuropeptide have structural similarity to somatostatin-14, binds and exerts its function via the somatostatin receptors (sst1-sst5). Cortistatin-14 acetate shows anticonvulsive, neuroprotective...
TP1570 Cortistatin-14 Somatostatin
Cortistatin-14, a neuropeptide structurally similar to growth inhibitor-14, has anticonvulsant and neuroprotective effects and impairs recognition memory consolidation in mice through activation of sst(2), growth hormone...
TP2236L Cortistatin-8 acetate Cortistatin-8 acetate(485803-62-1 Free base) GHSR
Cortistatin-8 acetate is a corticosteroid analog, a GHS-R antagonist with inhibitory effects on the growth hormone pro-secretin receptor.Cortistatin-8 acetate is a synthetic corticosteroid-derived ligand for the growth h...
T35662 Cortistatin-29 (1-13) (rat) (trifluoroacetate salt)
Cortistatin-29 (1-13) is a neuropeptide and cleavage product of cortistatin-29 , which is a cleavage product of procortistatin. Cortistatin-29 (1-13) corresponds to the first 13 amino acids of cortistatin-29.
T35663 Cortistatin-29 (rat) (trifluoroacetate salt)
Cortistatin-29 is a neuropeptide that is structurally similar to somatostatin-28. It is produced by cleavage of preprocortistatin to procortistatin, which is cleaved at dibasic amino acids to form cortistatin-29 and cort...
TP1188 Cortistatin 14, human, rat CST-14, human, rat
Cortistatin 14 is a somatastatin-like neuropeptide with neuronal depressant and sleep modulating properties. Cortistatin 14 is present primarily in the cortex and hippocampus.
TP1685 Cortistatin-14 TFA (186901-48-4 free base) Cortistatin-14 TFA
Cortistatin-14 is a neuropeptide have structural similarity to somatostatin-14. It is produced in the cortex and hippocampus of central nervous system.
T76034 Cortistatin-14 TFA
Cortistatin-14 (TFA), a neuropeptide resembling somatostatin-14 in structure, operates through interaction with somatostatin receptors (sst1-sst5). This compound exhibits anticonvulsive and neuroprotective effects alongs...
T76331 Cortistatin 29
Cortistatin 29, a neuropeptide, alleviates neuropathic pain and exhibits anti-fibrotic effects. It binds with high affinity to all somatostatin (SS) receptor subtypes, displaying IC 50 values of 2.8 nM for SSTR1, 7.1 nM ...
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