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Search Results for " arnt "

Targets

6

Compounds

3

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T81646 NPAS3-IN-1 Others
NPAS3-IN-1 is a potent inhibitor of NPAS3-ARNT heterodimerization, which regulates NPAS3 transcription by modulating the heterodimerization of NPAS3 with ARNT at the cellular level.
T67831 HIF-2α agonist 2 HIF/HIF Prolyl-Hydroxylase , HIF
HIF-2α agonist 2 is an HIF-2α agonist with an EC50 value of 1.68 μM for HIF-2α. HIF-2α agonist 2 can promote the stability of the ARNT A/B ring in the 3z structure of HIF-2a-ARNT complex without cytotoxicity to 786-o-Reh...
T61822 M1002 HIF
M1002 is a hypoxia-inducible factor-2 (HIF-2) agonist that enhances the affinity of HIF-2alpha and ARNT for transcriptional activation.M1002 alters the Tyr2 conformation of the HIF-281alpha PAS-B structural domain and ac...
T7802 M1001 HIF/HIF Prolyl-Hydroxylase , HIF
M1001 is a HIF-2α agonist.
T60539 KG-548
KG-548 is an ARNT/TACC3 disruptor as well as a HIF-1α inhibitor. KG-548 directly interferes with the formation of the ARNT/TACC3 complex by competitively binding the ARNT PAS-B domain with TACC3. ARNT is the aryl hydroca...
T69080 T1001
T1001 is an antagonist of hypoxia-inducible factor-2α subunit (HIF-2α) which displaces residue M252 from inside the HIF-2α PAS-B pocket toward the ARNT subunit to weaken heterodimerization.

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPH-00957 ARNT Protein, Human, Recombinant (His) Human P. pastoris (Yeast)
ARNT Protein, Human, Recombinant (His) is expressed in Yeast.
TMPH-02379 arnT Protein, Klebsiella pneumoniae, Recombinant (His) Klebsiella pneumoniae E. coli
Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antim...
TMPY-01709 HIF-1 alpha Protein, Human, Recombinant (His) Human E. coli
HIF-1 alpha, also known as HIF1A, contains 1 basic helix-loop-helix (bHLH) domain, 1 PAC (PAS-associated C-terminal) domain, and 2 PAS (PER-ARNT-SIM) domains. It is one of the two subunits of Hypoxia-inducible factor-1 (...
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