Home Tools
Log in
Cart

Search Result

Search Results for " y641n "

9

Compounds

Cat No. Product Name Synonyms Targets
T12428L PF-06726304 Histone Methyltransferase
PF-06726304 shows robust antitumor growth activity. PF-06726304 is an effective and selective EZH2 inhibitor. PF-06726304 inhibits wild-type and Y641N mutant EZH2 (Kis: 0.7 and 3.0 nM, respectively).
T6809 CPI-169 racemate CPI 169,CPI-169,CPI169 Epigenetic Reader Domain , Histone Methyltransferase
CPI-169 racemate (CPI 169) is a potent, and selective EZH2 inhibitor with IC50 of 0.24 nM, 0.51 nM, and 6.1 nM for EZH2 WT, EZH2 Y641N, and EZH1, respectively.
T12430 PF-06821497 Histone Methyltransferase
PF-06821497 is a selective inhibitor of EZH2 with significant tumor growth inhibition.
T79780 IHMT-EZH2-426 Histone Methyltransferase
IHMT-EZH2-426 (compound 38) is a potent, covalent degrader of EZH2, demonstrating IC50 values of 1.3 nM for EZH2 wild-type, 1.2 nM for EZH2-A687V, and 1.7-3.5 nM for EZH2-Y641F/Y641N/Y641S mutants. The compound effective...
T73246 EZH2-IN-7
EZH2-IN-7, a potent inhibitor of EZH2, addresses overexpression or mutations in the SET region (Y641F, Y641N, A687V, A677G point mutations) that cause an abnormal increase in H3K27me3, contributing to the proliferation o...
T64208 EZH2-IN-9
EZH2-IN-9 is a potent inhibitor of EZH2, whose overexpression or mutations in the SET region (Y641F, Y641N, A687V, A677G point mutations) cause abnormal elevations in H3K27me3 and contribute to the growth and development...
T64307 EZH2-IN-8
EZH2-IN-8 is a potent inhibitor of EZH2. EZH2-IN-8 has the potential to be used in the study of cancer diseases.
T12428 PF-06726304 acetate Histone Methyltransferase
PF-06726304 acetate is a selective inhibitor of EZH2, with robust antitumor growth activity.
T27069 CPI-169 CPI 169 (R),CPI-169 (R)
CPI-169 (R) is a novel and potent inhibitor of EZH2.
TargetMol