Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PF-06726304 acetate is a selective inhibitor of EZH2, with robust antitumor growth activity.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 mg | 4-5 weeks | $ 540.00 |
Description | PF-06726304 acetate is a selective inhibitor of EZH2, with robust antitumor growth activity. |
Targets&IC50 | EZH2 (Y641N):3.0 nM (ki), EZH2 (WT):0.7 nM (ki) |
In vitro | PF-06726304 inhibits the proliferation of Karpas-422 cells that harbor wild-type EZH2 (IC50 of 25 nM)[1]. |
In vivo | In a subcutaneous Karpas-422 xenograft model,PF-06726304 inhibits tumor growth and induces robust modulation of downstream biomarkers [1]. |
Molecular Weight | 506.38 |
Formula | C24H25Cl2N3O5 |
CAS No. | 2080306-28-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
PF-06726304 acetate 2080306-28-9 Chromatin/Epigenetic Histone Methyltransferase PF 06726304 Acetate PF-06726304 Acetate PF 06726304 acetate PF06726304 Acetate PF06726304 acetate inhibitor inhibit