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Search Results for " xz739 "

4

Compounds

Cat No. Product Name Synonyms Targets
T39909 XZ739 XZ739 PROTACs
XZ739 is a Cereblon-dependent PROTAC BCL-XL degrader, targeting a member of the Bcl-2 family, with a DC50 value of 2.5 nM in MOLT-4 cells after 16 hours of treatment. Additionally, XZ739 elicits cell death via caspase-me...
T39910 Desmorpholinyl Navitoclax-NH-Me Desmorpholinyl ABT-263-NH-Me,Desmorpholinyl Navitoclax-NH-Me BCL
Desmorpholinyl Navitoclax-NH-Me (Desmorpholinyl ABT-263-NH-Me) is a Bcl-xL inhibitor, which can be employed alongside a CRBN ligand to synthesize XZ739, a PROTAC BCL-XL degrader [1] [2].
T9382 Thalidomide-NH-C2-PEG3-OH H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-[[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethyl]amino]- E3 Ligase Ligand-Linker Conjugate
Thalidomide-NH-C2-PEG3-OH (H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-[[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethyl]amino]-) is an E3 ligase ligand-linker conjugate.
T39604 Thalidomide-NH-PEG4-Ms Thalidomide-NH-PEG4-Ms
Thalidomide-NH-PEG4-Ms is a conjugate that consists of a cereblon ligand based on Thalidomide and a linker molecule, which serves as a ligand-linker moiety for E3 ligase. This conjugate is specifically designed as a degr...
TargetMol