vegfa — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T12574	PTC299	Emvododstat,(4-chlorophenyl) (1S)-6-chloro-1-(4-methoxyphenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-2-carboxylate	VEGFR , Dehydrogenase
	PTC299 ((4-chlorophenyl) (1S)-6-chloro-1-(4-methoxyphenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-2-carboxylate) is an orally active inhibitor of VEGFA mRNA translation and selectively inhibits VEGF protein synthesis at t...		VEGFR , Dehydrogenase
T11153	EG00229		Others
	EG00229 is a neuropilin 1 (NRP1) receptor antagonist that selectively inhibits the binding of VEGF-A to the NRP1 b1 domain, achieving this inhibition with an IC50 value of 3 μM. It does not affect the binding of VEGF-A t...		Others
T60398	Dimethyl-bisphenol A
	Dimethyl-bisphenol A (DMBPA) is the potent inhibitor of HIF-1α. Dimethyl-Bisphenol A promotes degradation of HIF-1α protein by dissociating Hsp90 from HIF-1α. Dimethyl-bisphenol A can decrease the expression of Vegfa mRN...
T76987	Tarcocimab
	Tarcocimab (OG1953), a humanized IgG1-type anti-VEGFA monoclonal antibody, is utilized in research targeting conditions such as retinal vein occlusion (RVO) and wet age-related macular degeneration (AMD).
T76506	Coibamide A
	Coibamide A, an N-methyl-stabilized cytotoxic depsipeptide, exhibits potent antiproliferative activity alongside inducing autophagosome accumulation through an mTOR-independent mechanism and triggering apoptosis. Additio...
T69452	AG-13958 monohydrochloride
	AG-13958 monohydrochloride is the HCl salt of AG-13958 --- a VEGFA inhibitor potentially for the treatment of age-related macular degeneration. Neovascular AMD, a subtype characterized by the growth of new, pathologic bl...

Compounds

PTC299

T12574

Synonym: Emvododstat,(4-chlorophenyl) (1S)-6-chloro-1-(4-methoxyphenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-2-carboxylate

Target: VEGFR, Dehydrogenase

AG-13958 monohydrochloride

T69452

Synonym:

Target:

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPK-00823	VEGF165 Protein, Human, Recombinant (His & Avi)	Human	HEK293
	Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most a...
TMPJ-00865	VEGF121 Protein, Human, Recombinant (His)	Human	Human Cells
	Human VEGF121, also known as Vascular endothelial growth factor A, VEGFA, Vascular permeability factor, VPF and VEGF, is a homodimeric, heparin-binding glycoprotein which belongs to the platelet-derived growth factor (PD...
TMPH-03217	VEGFA Protein, Rabbit, Recombinant (His)	Rabbit	Yeast
	VEGFA Protein, Rabbit, Recombinant (His) is expressed in Yeast with N-terminal 6xHis tag. The predicted molecular weight is 51.7 kDa. Accession number: XP_002714743.1
TMPH-03131	VEGFA Protein, Pig, Recombinant (His)	Sus scrofa (Pig)	E. coli
	Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds t...
TMPH-03218	VEGFA Protein, Rabbit, Recombinant (His & SUMO)	Rabbit	E. coli
	VEGFA Protein, Rabbit, Recombinant (His & SUMO) is expressed in E. coli.
TMPK-00826	VEGF121 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most a...
TMPK-00825	VEGF121 Protein, Human, Recombinant (His & Avi)	Human	HEK293
	Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most a...
TMPK-00822	VEGF165 Protein, Human, Recombinant (His & Avi), FITC-Labeled	Human	HEK293
	Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most a...
TMPJ-00412	VEGFR1/FLT-1 Protein, Human, Recombinant (hFc)	Human	Human Cells
	Human Vascular endothelial growth factor receptor 1(VEGFR-1, FLT-1) is a member of the the class III subfamily of receptor tyrosine kinases (RTKs) and Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1 ...
TMPH-01721	C-Myc Protein, Human, Recombinant (Avi & His & MBP), Biotinylated	Human	E. coli
	Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promotin...
TMPH-01720	C-Myc Protein, Human, Recombinant (His)	Human	E. coli
	Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promotin...
TMPK-00645	VEGFR2/KDR Protein, Rhesus macaque, Recombinant (His)	Rhesus macaque	HEK293
	Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migratio...
TMPK-00454	VEGFR2/KDR Protein, Human, Recombinant (His & Avi)	Human	HEK293
	Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migratio...
TMPK-00451	VEGFR1/FLT-1 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	VEGFR1 (vascular endothelial growth factor receptor 1), also called Flt-1 (Fms-like tyrosine kinase), is a 180 kDa type I transmembrane glycoprotein in the class III subfamily of receptor tyrosine kinases (RTKs).yrosine-...
TMPK-00450	VEGFR1/FLT-1 Protein, Human, Recombinant (His & Avi)	Human	HEK293
	VEGFR1 (vascular endothelial growth factor receptor 1), also called Flt-1 (Fms-like tyrosine kinase), is a 180 kDa type I transmembrane glycoprotein in the class III subfamily of receptor tyrosine kinases (RTKs).yrosine-...