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Search Results for " topotecan "

5

Compounds

Cat No. Product Name Synonyms Targets
T5784 Topotecan NSC 609669,SKF 104864A Topoisomerase , Autophagy
Topotecan (NSC-609669) is a Topoisomerase I inhibitor,and is an antineoplastic agent used to treat ovarian cancer that works by inhibiting DNA topoisomerases.
T1174 Topotecan hydrochloride SKF 104864A,SKFS 104864A,NSC609699,Nogitecan HCl,NSC 609669,Topotecan HCl Apoptosis , Topoisomerase , Autophagy
Topotecan hydrochloride (NSC609699) is an antineoplastic agent used to treat ovarian cancer.
T63105 Topotecan hydrochloride hydrate
Topotecan hydrochloride hydrate is an orally active Topoisomerase I inhibitor with anticancer properties. topotecan hydrochloride hydrate is capable of blocking the cell cycle in G0/G1 and S phases and inducing apoptosis...
T71908 NU1085
NU1085 is a potent poly(ADP-ribose) polymerase (PARP) inhibitors have been developed that potentiate the cytotoxicity of ionizing radiation and anticancer drugs. The biological effects of NU1085 [Ki = 6 nM], in combinati...
T73411 PV-1019 NSC 744039
PV-1019 (NSC 744039) is a potent, selective inhibitor of Chk2, displaying an IC50 of 24 nM. It effectively inhibits Topotecan-induced Chk2 autophosphorylation and suppresses IR-induced apoptosis [1].
TargetMol