thelin — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T6672	Sitaxsentan sodium	TBC11251 sodium salt,TBC11251,Thelin,Sitaxentan sodium	Endothelin Receptor
	Sitaxsentan sodium (TBC11251 sodium salt) is a highly selective antagonist of endothelin A receptors.		Endothelin Receptor
T19309L1	Endothelin 1 (swine, human) acetate	Endothelin 1 (swine, human) acetate(117399-94-7 free base)	Endothelin Receptor
	Endothelin 1 (swine, human) acetate is a synthetic peptide with the sequence of human and swine Endothelin 1. Endothelin 1 is a potent endogenous vasoconstrictor and acts through two types of receptors ETA and ETB.		Endothelin Receptor
TP1174	Endothelin-2 (49-69), human	Human endothelin-2,Endothelin-2, human,Endothelin-2 (human, canine)	Others
	Endothelin-2 (49-69), human (Human endothelin-2) is a 21-amino acid vasoactive peptide that binds to G-protein-linked transmembrane receptors, ET-RA and ET-RB.		Others
T22540L	Ac-Endothelin-1 (16-21), human acetate		Others
	Ac-Endothelin-1 (16-21), human acetate, the principal peptide of the endothelin family, has been shown to have a variety of biological activities in both vascular and nonvascular tissues. The C-terminal fragment, which i...		Others
T1006	Propantheline bromide	Neopepulsan,Pro-Banthine,Neometantyl	AChR
	Propantheline bromide (Pro-Banthine) competitively antagonizes acetylcholine activity mediated by muscarinic receptors at neuroeffector sites on smooth muscle and exocrine gland cells. Propantheline Bromide is the bromid...		AChR
TP2143	Endothelin-2 (49-69), human TFA	Endothelin-2 (49-69) (human, canine) TFA,Human endothelin-2 TFA	Others
	Endothelin-2 (49-69), human (TFA) is a 21-amino acid vasoactive peptide that binds to ET-RA and ET-RB.		Others
TP2099	[Ala1,3,11,15]-Endothelin
	Selective ETB endothelin receptor agonist (IC50 values are 0.33 and 2200 nM for displacing [125I]-ET-1 from ETB and ETA receptors respectively).
T82886	Big endothelin-1 (rat 1-39)
	Big endothelin-1 (rat 1-39), a 39-residue peptide, induces a diuretic and natriuretic response in conscious Sprague-Dawley rats and elevates blood pressure in mice [1].
TP1512	[Ala1,3,11,15]-Endothelin TFA
	[Ala1,3,11,15]-Endothelin (TFA) is a highly selective for endothelin A (ETA) and endothelin B (ETB) receptor.[Ala1,3,11,15]-Endothelin is a selective ETB endothelin receptor agonist (IC50 values are 0.33 and 2200 nM for ...
T36479	Big Endothelin-1 (1-38), human
	Human Big ET-1 comprises residues 53-90 of the endothelin precursor (preproendothelin). Compared to the mature endothelin-1 (hET-1), the peptide show less vasoconstrictor activity in vitro, but similar pressor effects in...
T75772	[Ala1,3,11,15]-Endothelin (53-63) (TFA)
	[Ala1,3,11,15]-Endothelin (53-63) (TFA) is a selective ET B agonist with IC50 values ranging from 0.33 nM to 0.61 nM, demonstrating its preference for ET B receptors. It is utilized in the study of vasoconstriction.
TP1173	Endothelin 3 (Rat,Human) (TFA)	Endothelin-3, human, mouse, rabbit, rat TFA
	Endothelin-3, human, mouse, rabbit, rat TFA is a 21-amino acid vasoactive peptide that specifically interacts with G-protein-linked transmembrane receptors, ET-RA and ET-RB.
TP2246	Endothelin-1 (1-15), amide, human		Others
	Endothelin-1 is one of the there isoforms of endothelin (identified as ET-1, -2, -3) with varying regions of expression and binding to at least four known endothelin receptors, ETA, ETB1, ETB2 and ETC.		Others
T19309	Endothelin 1 (swine, human)		Others
	Endothelin 1 (swine, human), a synthetic peptide mirroring the sequence of both human and swine Endothelin 1, functions as a robust endogenous vasoconstrictor by interacting with two receptor types, ETA and ETB.		Others
TP1175	Endothelin-3, human, mouse, rabbit, rat	Endothelin 3 (Rat,Human)
	Endothelin-3, human, mouse, rabbit, rat , is a cyclic 21 amino acid peptide. It is an endogenous neuropeptide and potent vasoconstrictor.
T76564	Endothelin-1 (1-31) (Human)
	Endothelin-1 (1-31) (Human) is a powerful vasoconstrictor and agent for inducing hypertension, originating from the specific hydrolysis of big ET-1 by chymase [1].
T76081	Endothelin 1 (swine, human), Alexa Fluor 488-labeled
	Endothelin 1 (swine, human), Alexa Fluor 488-labeled, is a synthetic peptide corresponding to the sequence of human and swine Endothelin 1, a powerful endogenous vasoconstrictor, and is tagged with Alexa Fluor 488 for fl...
T76564L	Endothelin-1 (1-31) (Human) acetate
	Endothelin-1 (1-31) (Human) acetate, a potent vasoconstrictor and hypertensive agent, is produced through the selective hydrolysis of big ET-1 by chymase [1].
T75731	Endothelin 1 (swine, human) (TFA)
	Endothelin 1 (swine, human) (TFA) is a synthetic peptide mirroring the sequence of the potent endogenous vasoconstrictor found in both human and swine Endothelin 1. It operates via two receptor types, ET A and ET B [1].
T61453	Propantheline
	Propantheline is an orally active antagonist of muscarinic acetylcholine receptors (mAChRs), commonly employed to investigate smooth muscle dysfunction, hyperhidrosis, smooth muscle spasms or cramps in the stomach, intes...