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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T26282 | TNIK-IN-1 | TNIK-inhibitor-1,TNIK inhibitor 1 | Others |
TNIK-IN-1 is an inhibitor of Traf2- and Nck-interacting kinase (TNIK). | |||
T9556 | TNIK-IN-3 | Wnt/beta-catenin | |
TNIK-IN-3 is a highly potent and orally active inhibitor of Traf2- and Nck-interacting protein kinase (TNIK). It exhibits a strong selectivity for TNIK with an IC50 value of 0.026 μM. Additionally, TNIK-IN-3 demonstrates... | |||
T77660 | TINK-IN-1 | Wnt/beta-catenin | |
TINK-IN-1 is a selective and potent TNIK inhibitor (IC50: 8 nM).TINK-IN-1 inhibits colorectal cancer cell viability and can be used to study mental retardation. | |||
T68051 | Delequamine | RS 15385-197 | Adrenergic Receptor |
Delequamine (RS 15385-197) is a selective and potent TNIK inhibitor (IC50: 8 nM).TINK-IN-1 inhibits colorectal cancer cell viability and can be used to study mental retardation. | |||
T5093 | Pim1/AKK1-IN-1 | LKB1/AAK1 dual inhibitor,MDK-2275 | Pim , Hippo pathway |
Pim1/AKK1-IN-1 (LKB1/AAK1 dual inhibitor) is a potent multi-kinase inhibitor with Kd values of 35 nM/53 nM/75 nM/380 nM for Pim1/AKK1/MST2/LKB1 respectively, and also inhibits MPSK1 and TNIK. | |||
T80971 | TNIK-IN-6 | Others | |
TNIK-IN-6 (Compound 9) acts as an inhibitor of Traf2 and Nck-interacting kinase (TNIK), exhibiting an inhibitory concentration (IC50) of 0.93 μM, a kinase implicated in various neurological and psychiatric disorders [1] ... | |||
T79794 | TNIK&MAP4K4-IN-1 | Others | |
TNIK&MAP4K4-IN-1 (compound A-39) is a potent dual inhibitor targeting TNIK and MAP4K4/HGK, exhibiting IC50 values of 1.29 nM and <10 nM, respectively, in human hepatic stellate cell LX-2. This compound is applicable in t... | |||
T61396 | TNIK-IN-4 | Others | |
TNIK-IN-4, a powerful TNIK inhibitor, exhibits an IC50 value of 0.61 μM. Furthermore, it demonstrates inhibitory effects on the HCT116 cell line, which is representative of colorectal cancer [1]. | |||
T79908 | ON 108600 | Casein Kinase | |
ON 108600 is a chemical inhibitor targeting CK2 (Casein Kinase 2), TNIK, and DYRK1, demonstrating IC50 values of 0.016 μM and 0.007 μM for DYRK1A and DYRK1B, 0.028 μM for DYRK2, 0.05 μM and 0.005 μM for CK2α1 and CK2α2, ... |