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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T63012 | TM-1 | ||
TM-1 is a potent pyruvate dehydrogenase kinase (PDHK) inhibitor that inhibits the activity of PDHK1 (IC50: 2.97 μM) and PDHK2 (IC50: 5.2 μM). TM-1 blocks pyruvate dehydrogenase complex (PDHC) phosphorylation and inhibits... | |||
T4254 | TM5441 | PAI-1 , Apoptosis | |
TM5441 is an orally bioavailable inhibitor of plasminogen activator inhibitor 1 (PAI-1). | |||
T8962 | TM5007 | PAI-1 | |
TM5007 is a poent inhibitor of plasminogen activator inhibitor-1 (PAI-1; IC50 of 29 uM). | |||
T4255 | TM5275 sodium | TM5275 sodium salt | PAI-1 |
TM5275 sodium (TM5275 sodium salt) is an inhibitor of plasminogen activator inhibitor 1 (PAI-1). | |||
T10630 | BuChE-IN-TM-10 | TM-10 | AChR |
BuChE-IN-TM-10 (TM-10) is a potent inhibitor of butyrylcholinesterase (BuChE), exhibiting an IC50 of 8.9 nM. It effectively inhibits and disaggregates self-induced Aβ aggregation, displays significant antioxidant activit... | |||
T82491 | EGFR-IN-90 | EGFR | |
EGFR-IN-90 (compound 34), an orally active EGFR inhibitor, demonstrates potent activity against EGFRL858R/T790M/C797S with an IC50 of 5.1 nM and effectively inhibits the proliferation of the H1975-TM cell line carrying E... | |||
T75670 | Lacto-N-fucopentaose II | ||
Lacto-N-fucopentaose II (LNFP II), a sialyl-Lewis hapten of the human Lewis blood group determinant, serves as a monosialo-ganglioside/glycolipid and sialyl derivative, CA 19-9. It is recognized as a molecular tumor mark... | |||
T70763 | KR-67607 | ||
KR-67607, also known as NTX-101 is novel selective 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1) inhibitor. KR-67607 decreased 4-hydroxynonenal expression and increased antioxidant and mucus secretion in BAC-treated rat ... | |||
T73154 | EGFR-IN-70 | ||
EGFR-IN-70 is a potent EGFR inhibitor with IC 50 values of 23.6 and 307.5 nM for EGFR LR/TM/CS and EGFR WT , respectively. EGFR-IN-70 has anti-proliferative activity and suppresses phosphorylation of the EGFR . EGFR-IN-... | |||
T71119 | Netarsudil free base | ||
Netarsudil, also known as AR-11324, is a Rho-associated protein kinase inhibitor. Netarsudil is potential useful for treating glaucoma and/or reducing intraocular pressure. Netarsudil Increases Outflow Facility in Hum... |