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Search Results for " tgfb1 "

Targets

2

Compounds

27

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T80562 Nisevokitug NIS-793 TGF-beta/Smad
Nisevokitug (NIS-793) is an IgG2λ human monoclonal antibody that targets TGF-β (TGFB1/TGFB2). It is produced in CHO-K1 cells [1].
T77000 Cirevetmab
Cirevetmab (ZTS-00521426), a caninized monoclonal antibody targeting Canis lupus familiaris TGFB1, is classified as an immunoglobulin G2-kappa. It functions as an immunomodulator [1].

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPJ-00249 TGF beta 1 Protein, Human, Recombinant (Avi), Biotinylated Human Human Cells
Transforming Growth Factor β-1 (TGFβ-1) is a secreted protein which belongs to the TGF-β family. TGFβ-1 is abundantly expressed in bone, articular cartilage and chondrocytes and is increased in osteoarthritis (OA). TGFβ-...
TMPJ-00772 Latent TGF-beta 1 Protein, Mouse, Recombinant (His & Avi), Biotinylated Mouse Human Cells
Transforming growth factor beta (TGFβ) is a multifunctional cytokine that regulates cell growth, differentiation, adhesion, migration and death dependent on cell type, developmental stage, or tissue conditions. There are...
TMPJ-00622 Latent TGF-beta 1 Protein, Cynomolgus, Recombinant (His) Cynomolgus Human Cells
Transforming growth factor beta (TGFβ) is a multifunctional cytokine that regulates cell growth, differentiation, adhesion, migration and death dependent on cell type, developmental stage, or tissue conditions. There are...
TMPJ-00250 LAP (TGF-beta 1) Protein, Human, Recombinant (His & Avi), Biotinylated Human Human Cells
Transforming growth factor beta (TGFβ) family members are secreted in inactive complexes with a latency-associated peptide (LAP), a protein derived from the N-terminal region of the TGFβ gene product. Extracellular activ...
TMPJ-00771 TGF beta 1 Protein, Mouse/Rat, Recombinant Mouse,Rat Human Cells
Transforming growth factor beta 1 (TGFβ1) is the prototype of a growing superfamily of peptide growth factors and plays a prominent role in a variety of cellular processes, including cell-cycle progression, cell differen...
TMPY-03802 IL-17F Protein, Human, Recombinant (aa 31-163) Human E. coli
Interleukin-17F (IL-17F) is a cytokine that shares sequence similarity with IL17. The most notable role of IL-17 is its involvement in inducing and mediating proinflammatory responses. IL-17 is commonly associated with a...
TMPH-01051 CILP Protein, Human, Recombinant (His & Myc) Human Baculovirus
Probably plays a role in cartilage scaffolding. May act by antagonizing TGF-beta1 (TGFB1) and IGF1 functions. Has the ability to suppress IGF1-induced proliferation and sulfated proteoglycan synthesis, and inhibits ligan...
TMPH-02231 NRROS Protein, Human, Recombinant (E. coli, His & Myc) Human E. coli
Key regulator of transforming growth factor beta-1 (TGFB1) specifically required for microglia function in the nervous system. Required for activation of latent TGF-beta-1 in macrophages and microglia: associates specifi...
TMPH-02230 NRROS Protein, Human, Recombinant (His & Myc) Human Baculovirus
Key regulator of transforming growth factor beta-1 (TGFB1) specifically required for microglia function in the nervous system. Required for activation of latent TGF-beta-1 in macrophages and microglia: associates specifi...
TMPH-02803 NRROS Protein, Mouse, Recombinant (His) Mouse E. coli
Key regulator of transforming growth factor beta-1 (TGFB1) specifically required for microglia function in the nervous system. Required for activation of latent TGF-beta-1 in macrophages and microglia: associates specifi...
TMPH-02594 MMP-13 Protein, Mouse, Recombinant (His) Mouse E. coli
Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the hig...
TMPH-02959 Tsukushi Protein, Mouse, Recombinant (His & Myc) Mouse E. coli
Contributes to various developmental events and other processes such as wound healing and cholesterol homeostasis through its interactions with multiple signaling pathways. Wnt signaling inhibitor which competes with WNT...
TMPJ-01093 HYAL1 Protein, Human, Recombinant (His) Human Human Cells
Hyaluronidase-1 (HYAL1) is a secreted lysosomal hyaluronidase that belongs to the glycosyl hydrolase 56 family. HYAL1 contains one EGF-like domain and is highly expressed in the liver, kidney, and heart, but it is weakly...
TMPJ-01085 DPT Protein, Human, Recombinant (hFc & His) Human Human Cells
Dermatopontin, also known as Tyrosine-rich acidic matrix protein, TRAMP and DPT, is a secreted protein which belongs to the dermatopontin family. DPT is expressed in various tissues, such as fibroblasts, heart, skeletal ...
TMPH-01331 FERMT2 Protein, Human, Recombinant (His) Human E. coli
Scaffolding protein that enhances integrin activation mediated by TLN1 and/or TLN2, but activates integrins only weakly by itself. Binds to membranes enriched in phosphoinositides. Enhances integrin-mediated cell adhesio...
TMPJ-01369 DPT Protein, Mouse, Recombinant (hFc) Mouse Human Cells
Dermatopontin is a widely expressed noncollagenous protein component of the extracellular matrix. It is a 22 kDa molecule that is tyrosine sulfated but not glycosylated. Dermatopontin is down regulated in fibrotic growth...
TMPJ-00633 IL-17F Protein, Cynomolgus, Recombinant (His) Cynomolgus Human Cells
Interleukin-17F (IL-17F) exists in a disulfide-linked heterodimer that belongs to the IL-17 family. IL-17F is expressed in activated, but not resting, CD4+ T-cells and activated monocytes. IL-17F has been shown to stimul...
TMPJ-00573 IL-17F Protein, Human, Recombinant (His) Human Human Cells
Interleukin-17F (IL-17F) exists in a disulfide-linked heterodimer that belongs to the IL-17 family. IL-17F is expressed in activated, but not resting, CD4+ T-cells and activated monocytes. IL-17F has been shown to stimul...
TMPH-01269 SMURF2 Protein, Human, Recombinant (His) Human E. coli
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Interacts with SMAD7 to trigger SMA...
TMPY-01264 15-PGDH Protein, Human, Recombinant (His) Human E. coli
15-hydroxyprostaglandin dehydrogenase [NAD+], also known as Prostaglandin dehydrogenase 1, HPGD, and PGDH1, is a member of the short-chain dehydrogenases/reductases (SDR) family. Prostaglandins (PGs) play a key role in t...
TMPY-02273 15-PGDH Protein, Mouse, Recombinant (His) Mouse E. coli
15-hydroxyprostaglandin dehydrogenase [NAD+], also known as Prostaglandin dehydrogenase 1, HPGD, and PGDH1, is a member of the short-chain dehydrogenases/reductases (SDR) family. Prostaglandins (PGs) play a key role in t...
TMPY-01966 IL-17F Protein, Mouse, Recombinant Mouse E. coli
Interleukin-17F (IL-17F) is a cytokine that shares sequence similarity with IL17. The most notable role of IL-17 is its involvement in inducing and mediating proinflammatory responses. IL-17 is commonly associated with a...
TMPY-01957 IL-17F Protein, Mouse, Recombinant (His) Mouse HEK293
Interleukin-17F (IL-17F) is a cytokine that shares sequence similarity with IL17. The most notable role of IL-17 is its involvement in inducing and mediating proinflammatory responses. IL-17 is commonly associated with a...
TMPY-00460 IL-17F Protein, Rat, Recombinant (His) Rat Baculovirus-Insect Cells
Interleukin-17F (IL-17F) is a cytokine that shares sequence similarity with IL17. The most notable role of IL-17 is its involvement in inducing and mediating proinflammatory responses. IL-17 is commonly associated with a...
TMPY-05461 IL-17F Protein, Human, Recombinant (His), Biotinylated Human HEK293
Interleukin-17F (IL-17F) is a cytokine that shares sequence similarity with IL17. The most notable role of IL-17 is its involvement in inducing and mediating proinflammatory responses. IL-17 is commonly associated with a...
TMPH-03764 YAP1 Protein, Human, Recombinant (His) Human Yeast
Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor su...
TMPY-01898 IL-17F Protein, Human, Recombinant (aa 31-163, His) Human HEK293
Interleukin-17F (IL-17F) is a cytokine that shares sequence similarity with IL17. The most notable role of IL-17 is its involvement in inducing and mediating proinflammatory responses. IL-17 is commonly associated with a...
TGF beta 1 Protein, Human, Recombinant (Avi), Biotinylated
TMPJ-00249
Species: Human
Expression System: Human Cells
Latent TGF-beta 1 Protein, Mouse, Recombinant (His & Avi), Biotinylated
TMPJ-00772
Species: Mouse
Expression System: Human Cells
Latent TGF-beta 1 Protein, Cynomolgus, Recombinant (His)
TMPJ-00622
Species: Cynomolgus
Expression System: Human Cells
LAP (TGF-beta 1) Protein, Human, Recombinant (His & Avi), Biotinylated
TMPJ-00250
Species: Human
Expression System: Human Cells
TGF beta 1 Protein, Mouse/Rat, Recombinant
TMPJ-00771
Species: Mouse,Rat
Expression System: Human Cells
IL-17F Protein, Human, Recombinant (aa 31-163)
TMPY-03802
Species: Human
Expression System: E. coli
CILP Protein, Human, Recombinant (His & Myc)
TMPH-01051
Species: Human
Expression System: Baculovirus
NRROS Protein, Human, Recombinant (E. coli, His & Myc)
TMPH-02231
Species: Human
Expression System: E. coli
NRROS Protein, Human, Recombinant (His & Myc)
TMPH-02230
Species: Human
Expression System: Baculovirus
NRROS Protein, Mouse, Recombinant (His)
TMPH-02803
Species: Mouse
Expression System: E. coli
MMP-13 Protein, Mouse, Recombinant (His)
TMPH-02594
Species: Mouse
Expression System: E. coli
Tsukushi Protein, Mouse, Recombinant (His & Myc)
TMPH-02959
Species: Mouse
Expression System: E. coli
HYAL1 Protein, Human, Recombinant (His)
TMPJ-01093
Species: Human
Expression System: Human Cells
DPT Protein, Human, Recombinant (hFc & His)
TMPJ-01085
Species: Human
Expression System: Human Cells
FERMT2 Protein, Human, Recombinant (His)
TMPH-01331
Species: Human
Expression System: E. coli
DPT Protein, Mouse, Recombinant (hFc)
TMPJ-01369
Species: Mouse
Expression System: Human Cells
IL-17F Protein, Cynomolgus, Recombinant (His)
TMPJ-00633
Species: Cynomolgus
Expression System: Human Cells
IL-17F Protein, Human, Recombinant (His)
TMPJ-00573
Species: Human
Expression System: Human Cells
SMURF2 Protein, Human, Recombinant (His)
TMPH-01269
Species: Human
Expression System: E. coli
15-PGDH Protein, Human, Recombinant (His)
TMPY-01264
Species: Human
Expression System: E. coli
15-PGDH Protein, Mouse, Recombinant (His)
TMPY-02273
Species: Mouse
Expression System: E. coli
IL-17F Protein, Mouse, Recombinant
TMPY-01966
Species: Mouse
Expression System: E. coli
IL-17F Protein, Mouse, Recombinant (His)
TMPY-01957
Species: Mouse
Expression System: HEK293
IL-17F Protein, Rat, Recombinant (His)
TMPY-00460
Species: Rat
Expression System: Baculovirus-Insect Cells
IL-17F Protein, Human, Recombinant (His), Biotinylated
TMPY-05461
Species: Human
Expression System: HEK293
YAP1 Protein, Human, Recombinant (His)
TMPH-03764
Species: Human
Expression System: Yeast
IL-17F Protein, Human, Recombinant (aa 31-163, His)
TMPY-01898
Species: Human
Expression System: HEK293
TargetMol