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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T28137 | NC9 TG2 inhibitor | NC 9,NC-9 TG2 inhibitor,NC9 | |
NC9 is an irreversible inhibitor of transglutaminase 2 (TG2) and also inhibits Factor XIIIA (FXIIIA). | |||
T70413 | TG2-IN-3h | ||
TG2-IN-3h is a highly selective, potent, cell-permeable fluorescent irreversible tissue transglutaminase (tg2) inhibitor | |||
T29086 | VA5 TG2 inhibitor | VA5,VA-5,VA 5 | |
VA5 is an transamidase inhibitor by direct binding at the transamidase site. VA5 also inhibits GTP-binding activities. It interaction at the transamidase site locks the protein in the extended/open conformation to disorg... | |||
T69933 | VA4 TG2 inhibitor | ||
VA4 is a novel irreversible TG2 transamidase site-specific inhibitor. | |||
T26494 | AA10 TG2 inhibitor | AA 10,AA10,AA-10 | |
AA10 is an irreversible inhibitor of transglutaminase 2 (TG2). | |||
T83855 | TG2-179-1 | ||
TG2-179-1 is a BRCA1-associated protein 1 (BAP1) inhibitor that effectively hampers BAP1's deubiquitinase activity in cell-free assays at concentrations between 25 µM and 1.5 mM. This compound exhibits cytotoxicity towar... | |||
T69878 | AA9 TG2 inhibitor | ||
AA9 is a novel transglutaminase (TG2) inhibitor. | |||
T79505 | PROTAC TG2 degrader-1 | PROTACs | |
PROTAC TG2 Degrader-1 (Compound 11) is a VHL-based PROTAC that targets tissue transglutaminase (TG2) and exhibits a binding affinity with a K D of 68.9 μM. This compound effectively decreases TG2 levels in ovarian cancer... | |||
T79315 | PROTAC TG2 degrader-2 | PROTACs | |
PROTAC TG2 degrader-2 (compound 7) is a selective competitive degrader of Transglutaminase 2 (TG2), exhibiting a dissociation constant (Kd) greater than 100 μM. It inhibits cell migration and reduces TG2 levels in ovaria... | |||
T70412 | PNU-145156E free base | ||
PNU-145156E free base is an angiogenesis inhibitor. | |||
T67865 | BJJF078 | Glutaminase | |
BJJF078, an aminopiperidine derivative, is a potent inhibitor of recombinant human and mouse glutamine aminotransferase (TG2) activity, with IC50 values of 41 and 54 nM for human and mouse glutamine aminotransferase, res... | |||
T17289 | ZED-1227 | ZED-101,TAK-227 | Others , Glutaminase |
ZED-1227 (TAK-227) is an orally active, selective and potent transglutaminase 2 (TG2) inhibitor with anticancer activity that blocks inflammation-induced TG2 expression and activation for the treatment of Celiac Disease. | |||
T13783 | MT-4 | Others | |
MT-4 inhibits the adhesion of ovarian cancer (OC) cells to the peritoneum. | |||
T26265 | TG53 | TG-53,TG 53 | |
TG53 is a tissue transglutaminase (TG2) and fibronectin (FN) protein-protein interaction inhibitor. | |||
T71477 | CP4d inhibitor | ||
CP4d is a novel reversible tg2 transamidase site-specific inhibitor | |||
T76951 | Zampilimab | ||
Zampilimab (UCB-7858), a monoclonal antibody targeting transglutaminase 2 (TG2), exhibits potential applications in renal transplantation [1] [2]. |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01355 | Transglutaminase 2/TGM2 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
Protein-glutamine gamma-glutamyltransferase 2, also known as Tissue transglutaminase, Transglutaminase C, Transglutaminase-2, and TGM2, is a member of the transglutaminase superfamily. TGM2 plays a role in cell growth an... |