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Search Results for " tg2 "

16

Compounds

1

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T28137 NC9 TG2 inhibitor NC 9,NC-9 TG2 inhibitor,NC9
NC9 is an irreversible inhibitor of transglutaminase 2 (TG2) and also inhibits Factor XIIIA (FXIIIA).
T70413 TG2-IN-3h
TG2-IN-3h is a highly selective, potent, cell-permeable fluorescent irreversible tissue transglutaminase (tg2) inhibitor
T29086 VA5 TG2 inhibitor VA5,VA-5,VA 5
VA5 is an transamidase inhibitor by direct binding at the transamidase site. VA5 also inhibits GTP-binding activities. It interaction at the transamidase site locks the protein in the extended/open conformation to disorg...
T69933 VA4 TG2 inhibitor
VA4 is a novel irreversible TG2 transamidase site-specific inhibitor.
T26494 AA10 TG2 inhibitor AA 10,AA10,AA-10
AA10 is an irreversible inhibitor of transglutaminase 2 (TG2).
T83855 TG2-179-1
TG2-179-1 is a BRCA1-associated protein 1 (BAP1) inhibitor that effectively hampers BAP1's deubiquitinase activity in cell-free assays at concentrations between 25 µM and 1.5 mM. This compound exhibits cytotoxicity towar...
T69878 AA9 TG2 inhibitor
AA9 is a novel transglutaminase (TG2) inhibitor.
T79505 PROTAC TG2 degrader-1 PROTACs
PROTAC TG2 Degrader-1 (Compound 11) is a VHL-based PROTAC that targets tissue transglutaminase (TG2) and exhibits a binding affinity with a K D of 68.9 μM. This compound effectively decreases TG2 levels in ovarian cancer...
T79315 PROTAC TG2 degrader-2 PROTACs
PROTAC TG2 degrader-2 (compound 7) is a selective competitive degrader of Transglutaminase 2 (TG2), exhibiting a dissociation constant (Kd) greater than 100 μM. It inhibits cell migration and reduces TG2 levels in ovaria...
T70412 PNU-145156E free base
PNU-145156E free base is an angiogenesis inhibitor.
T67865 BJJF078 Glutaminase
BJJF078, an aminopiperidine derivative, is a potent inhibitor of recombinant human and mouse glutamine aminotransferase (TG2) activity, with IC50 values of 41 and 54 nM for human and mouse glutamine aminotransferase, res...
T17289 ZED-1227 ZED-101,TAK-227 Others , Glutaminase
ZED-1227 (TAK-227) is an orally active, selective and potent transglutaminase 2 (TG2) inhibitor with anticancer activity that blocks inflammation-induced TG2 expression and activation for the treatment of Celiac Disease.
T13783 MT-4 Others
MT-4 inhibits the adhesion of ovarian cancer (OC) cells to the peritoneum.
T26265 TG53 TG-53,TG 53
TG53 is a tissue transglutaminase (TG2) and fibronectin (FN) protein-protein interaction inhibitor.
T71477 CP4d inhibitor
CP4d is a novel reversible tg2 transamidase site-specific inhibitor
T76951 Zampilimab
Zampilimab (UCB-7858), a monoclonal antibody targeting transglutaminase 2 (TG2), exhibits potential applications in renal transplantation [1] [2].

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-01355 Transglutaminase 2/TGM2 Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
Protein-glutamine gamma-glutamyltransferase 2, also known as Tissue transglutaminase, Transglutaminase C, Transglutaminase-2, and TGM2, is a member of the transglutaminase superfamily. TGM2 plays a role in cell growth an...
TargetMol