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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T13892 | SNIPER(TACC3)-2 | Others | |
SNIPER(TACC3)-2 targets TACC3 protein degradation via the ubiquitin-proteasome pathway. It induces cancer cell death. | |||
T13891 | SNIPER(TACC3)-1 | Others | |
SNIPER(TACC3)-1 targets TACC3 protein degradation via the ubiquitin-proteasome pathway.It induces cancer cell death. | |||
T72631 | TACC3 inhibitor 1 | ||
TACC3 inhibitor 1 is a potent TACC3 inhibitor that can cross the blood-brain barrier, inducing apoptosis and cell cycle arrest at the G2/M phase, as well as the generation of intracellular ROS (reactive oxygen species). ... | |||
T74462 | SNIPER(TACC3)-11 | ||
SNIPER(TACC3)-11 is a potent degrader of the FGFR3-TACC3 protein, effectively diminishing its levels and inhibiting the proliferation of cancer cells positive for FGFR3-TACC3 [1]. | |||
T81142 | SNIPER(TACC3)-1 hydrochloride | SNIPERs | |
SNIPERTACC3-1 hydrochloride, an IAP ligand-based compound, selectively degrades the TACC3 protein through the ubiquitin-proteasome pathway, thereby inducing cancer cell apoptosis [1]. | |||
T81141 | SNIPER(TACC3)-2 hydrochloride | SNIPERs | |
SNIPER(TACC3)-2 hydrochloride is a compound that induces degradation of the TACC3 protein through the ubiquitin-proteasome pathway by exploiting an IAP ligand, leading to the induction of cancer cell death [1]. | |||
T8492 | BO-264 | Apoptosis , FGFR | |
BO-264 is a highly potent and orally active inhibitor of transforming acidic coiled-coil 3 (TACC3, IC50 of 188 nM and a Kd of 1.5 nM). | |||
T4968 | KHS 101 | Microtubule Associated | |
KHS101 is a novel inhibitor of transforming acidic coiled-coil protein 3 (TACC3). It is a selective inducer of neuronal differentiation. | |||
T5170 | KHS101 hydrochloride | FGFR , Microtubule Associated | |
KHS101 is a TACC3 inhibitor and can selectively induce a neuronal differentiation phenotype. | |||
T60539 | KG-548 | ||
KG-548 is an ARNT/TACC3 disruptor as well as a HIF-1α inhibitor. KG-548 directly interferes with the formation of the ARNT/TACC3 complex by competitively binding the ARNT PAS-B domain with TACC3. ARNT is the aryl hydroca... |