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Search Results for " steroid sulfatase-in-1 "

10

Compounds

Cat No. Product Name Synonyms Targets
T61687 Steroid sulfatase-IN-1
Steroid sulfatase-IN-1 is a highly potent and orally active inhibitor of the enzyme Steroid sulfatase, with an impressive IC50 value of 1.71 μM. This compound exhibits notable antitumor activity, achieving a TGI (tumor g...
T61716 Steroid sulfatase/17β-HSD1-IN-1
Steroid sulfatase/17β-HSD1-IN-1 is a highly effective inhibitor of both steroid sulfatase and 17β-hydroxysteroid dehydrogenase type 1 (17β-HSD1) activities, displaying an IC50 value of 28 nM against cellular human steroi...
T61979 Steroid sulfatase/17β-HSD1-IN-4
Steroid sulfatase/17β-HSD1-IN-4 (compound 37) is a potent dual inhibitor of steroid sulfatase ( STS ) and 17β-hydroxysteroid dehydrogenase type 1 ( 17β HSD1 ). Steroid sulfatase/17β-HSD1-IN-4 irreversibly inhibits hSTS a...
T62236 Steroid sulfatase/17β-HSD1-IN-3
Steroid sulfatase/17β-HSD1-IN-3 (compound 19) is a dual inhibitor of steroid sulfatase (STS) and 17β-hydroxysteroid dehydrogenase type 1 (17β HSD1). Steroid sulfatase/17β-HSD1-IN-3 can be used to study endometriosis and ...
T61212 Steroid sulfatase-IN-2
Steroid sulfatase-IN-2 is an active inhibitor of steroid sulfatase (STS), demonstrating an IC50 value of 109.5 nM. Its potential application lies in hormone-dependent cancer research, specifically estrogen-dependent brea...
T81090 Steroid sulfatase-IN-6
Steroid Sulfatase-IN-6 (Compound 10c) serves as an irreversible steroid sulfatase (STS) inhibitor, exhibiting a K i value of 0.4 nM against human placenta STS, and is applicable in tumor disease research [1].
T81089 Steroid sulfatase-IN-7
Steroid sulfatase-IN-7 is an irreversible inhibitor of steroid sulfatase (STS), demonstrating potent activity with an IC50 of 0.05 nM against human placental STS, rendering it suitable for application in cancer research ...
T61686 Steroid sulfatase-IN-3
Steroid sulfatase-IN-3 (compound 1q) is a highly effective Steroid sulfatase (STS) inhibitor, exhibiting an IC 50 value of 25.8 nM. This compound also demonstrates antiproliferative properties against T-47D estrogen-depe...
T81091 Steroid sulfatase-IN-5
Steroid sulfatase-IN-5 (compound 10b), an inhibitor of steroid sulfatase (STS) with an IC50 of 0.32 nM, effectively suppresses T-47D breast cancer cell proliferation, demonstrating an IC50 value of 35.7 μM. This compound...
T81092 Steroid sulfatase/17β-HSD1-IN-5
Steroid sulfatase/17β-HSD1-IN-5 serves as an irreversible inhibitor of steroid sulfatase (STS) and a reversible, selective inhibitor of 7β-hydroxysteroid dehydrogenase type1 (17β-HSD1), exhibiting IC50 values of 43 nM fo...
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