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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T4527 | Seclidemstat | SP-2577 | Histone Demethylase |
Seclidemstat (SP-2577) is an effective LSD1 inhibitor, with a mean IC50 of 127 nM. | |||
T10616 | BRM/BRG1 ATP Inhibitor-1 | Epigenetic Reader Domain | |
BRM/BRG1 ATP Inhibitor-1 is an allosteric dual Brahma homolog (BRM)/SWI/SNF related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 (SMARCA2) and BRG1/SMARCA4 ATPase activity inhibitor (IC50... | |||
T39954 | AU-15330 | Epigenetic Reader Domain , PROTACs | |
AU-15330 is a protein hydrolysis-targeted chimeric (PROTAC) degrader of the SWI/SNF ATPase subunits SMARCA2 and SMARCA4.AU-15330 potently inhibits tumor growth in a prostate cancer xenograft model and acts synergisticall... | |||
T39439 | Seclidemstat mesylate | SP-2577 mesylate | |
Seclidemstat mesylate (SP-2577) is a highly effective and reversible inhibitor of KDM1A (LSD1), with a Ki of 31 nM and an IC 50 of 13 nM. It demonstrates significant potential in promoting antitumor immunity in switch/su... |