20
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T18719 | SPP | Others | |
SPP is a cleavable linker that can be used to form antibody-coupled compounds with therapeutic effects on cancer. | |||
T16923 | SPP-86 | c-RET | |
SPP-86 is an effective and selective cell-permeable inhibitor of RET tyrosine kinase with an IC50 of 8 nM. | |||
T40761 | NO2-SPP-sulfo | NO2-SPP-sulfo | |
NO2-SPP-sulfo is a cleavable linker vital in ADC synthesis. NO2-SPP-sulfo joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimiz... | |||
TQ0282 | Avosentan | SPP-301,Ro 67-0565 | Endothelin Receptor |
Avosentan (Ro 67-0565) is an effective and selective antagonist of the endothelin receptor (ETA receptor). | |||
T18507 | NO2-SPP | Others | |
NO2-SPP is a cleavable linker that is used for making antibody-drug conjugate (ADC). | |||
T17836 | DMAC-SPP | Others | |
DMAC-SPP is a cleavable linker vital in ADC synthesis. DMAC-SPP joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC ef... | |||
T18718 | SPP-DM1 | Others | |
SPP-DM1, a drug-linker conjugate for antibody-drug conjugates (ADC), demonstrates potent antitumor activity. It comprises DM1 (a potent microtubule-disrupting agent) connected through the ADC linker SPP[1]. | |||
T18734 | Sulfo-SPP | Others | |
Sulfo-SPP is a heterobifunctional, thiol-cleavable and membrane impermeable crosslinker. | |||
T1520 | Aliskiren hemifumarate | CGP 60536,SPP 100,CGP60536B | RAAS , Autophagy |
Aliskiren hemifumarate (CGP60536B) is an orally active nonpeptide renin inhibitor with antihypertensive activity. | |||
T18724 | Sulfo-DMAC-SPP | Others | |
Sulfo-DMAC-SPP is an ADC linker employed for the synthesis of antibody-drug conjugates (ADCs) [1]. | |||
T18506 | NO2-SPP-sulfo-Me | Others | |
NO2-SPP-sulfo-Me is a cleavable linker utilized in the synthesis of antibody-drug conjugates (ADC)[1]. | |||
T72526 | Aliskiren fumarate | CGP 60536 fumarate,SPP 100 fumarate,CGP 60536 fumarate ; CGP60536B fumarate ; SPP 100 fumarate,CGP60536B fumarate | |
Aliskiren fumarate, an orally active, highly potent, and selective renin inhibitor with an IC50 of 1.5 nM, is utilized in the research of hypertension, cardiovascular diseases, and cancer cachexia. | |||
T0909 | Nalidixic acid | NSC-82174 | Topoisomerase , Antibacterial , Antibiotic |
Nalidixic acid (NSC-82174) is a synthetic 1, 8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of bacterial DNA GYRASE. | |||
T10282 | Aliskiren D6 Hydrochloride | SPP 100 D6 Hydrochloride,CGP60536B D6 Hydrochloride,CGP 60536 D6 Hydrochloride | Others |
Aliskiren (CGP 60536) D6 Hydrochloride is a deuterium-labeled Aliskiren. Aliskiren hemifumarate is a direct and orally active renin inhibitor (IC50: 1.5 nM). | |||
T19187 | Aliskiren D6 hemifumarate | CGP 60536 D6 hemifumarate,SPP 100 D6 hemifumarate,CGP60536B D6 hemifumarate | RAAS |
Aliskiren (CGP 60536) D6 hemifumarate is a deuterium-labeled Aliskiren hemifumarate. Aliskiren hemifumarate is a direct and orally active renin inhibitor (IC50: 1.5 nM). | |||
T0909L | Nalidixic acid sodium salt | Baktogram,Sodium nalidixate | Topoisomerase , Antibacterial , Antibiotic |
Nalidixic acid sodium salt (Baktogram) is an antimicrobial agent with a limited bacteriocidal spectrum. | |||
T23859 | CaspPro | C-2,C 2,Casp-Pro,Casp Pro,C2 | |
CaspPro is a selective activator of caspase 8 that acts by potentiating TRAIL-induced cell death. | |||
T81112 | SPPHPSPAFSPAFDNLYYWDQ | ||
SPPHPSPAFSPAFDNLYYWDQ is a multi-epitope class II rat HER2/neu peptide applicable in the investigation of class II HER2-DC1 vaccine studies [1]. | |||
T76367 | VSPPLTLGQLLS | ||
VSPPLTLGQLLS, also known as peptide P3, is a small peptide that serves as an inhibitor of FGFR3, effectively suppressing FGFR3 phosphorylation. It hinders 9-cisRA-induced tracheal lymphangiogenesis and impedes lymphatic ... | |||
T78442 | TSPP tetrasodium | ||
TSPP tetrasodium, a photosensitizer, has demonstrated significant efficacy in the in vivo regression of cancer and microbial infections (Ex: 413 nm, Em: 640 nm) [1][2]. |