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20

Compounds

Cat No. Product Name Synonyms Targets
T18719 SPP Others
SPP is a cleavable linker that can be used to form antibody-coupled compounds with therapeutic effects on cancer.
T16923 SPP-86 c-RET
SPP-86 is an effective and selective cell-permeable inhibitor of RET tyrosine kinase with an IC50 of 8 nM.
T40761 NO2-SPP-sulfo NO2-SPP-sulfo
NO2-SPP-sulfo is a cleavable linker vital in ADC synthesis. NO2-SPP-sulfo joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimiz...
TQ0282 Avosentan SPP-301,Ro 67-0565 Endothelin Receptor
Avosentan (Ro 67-0565) is an effective and selective antagonist of the endothelin receptor (ETA receptor).
T18507 NO2-SPP Others
NO2-SPP is a cleavable linker that is used for making antibody-drug conjugate (ADC).
T17836 DMAC-SPP Others
DMAC-SPP is a cleavable linker vital in ADC synthesis. DMAC-SPP joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC ef...
T18718 SPP-DM1 Others
SPP-DM1, a drug-linker conjugate for antibody-drug conjugates (ADC), demonstrates potent antitumor activity. It comprises DM1 (a potent microtubule-disrupting agent) connected through the ADC linker SPP[1].
T18734 Sulfo-SPP Others
Sulfo-SPP is a heterobifunctional, thiol-cleavable and membrane impermeable crosslinker.
T1520 Aliskiren hemifumarate CGP 60536,SPP 100,CGP60536B RAAS , Autophagy
Aliskiren hemifumarate (CGP60536B) is an orally active nonpeptide renin inhibitor with antihypertensive activity.
T18724 Sulfo-DMAC-SPP Others
Sulfo-DMAC-SPP is an ADC linker employed for the synthesis of antibody-drug conjugates (ADCs) [1].
T18506 NO2-SPP-sulfo-Me Others
NO2-SPP-sulfo-Me is a cleavable linker utilized in the synthesis of antibody-drug conjugates (ADC)[1].
T72526 Aliskiren fumarate CGP 60536 fumarate,SPP 100 fumarate,CGP 60536 fumarate ; CGP60536B fumarate ; SPP 100 fumarate,CGP60536B fumarate
Aliskiren fumarate, an orally active, highly potent, and selective renin inhibitor with an IC50 of 1.5 nM, is utilized in the research of hypertension, cardiovascular diseases, and cancer cachexia.
T0909 Nalidixic acid NSC-82174 Topoisomerase , Antibacterial , Antibiotic
Nalidixic acid (NSC-82174) is a synthetic 1, 8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of bacterial DNA GYRASE.
T10282 Aliskiren D6 Hydrochloride SPP 100 D6 Hydrochloride,CGP60536B D6 Hydrochloride,CGP 60536 D6 Hydrochloride Others
Aliskiren (CGP 60536) D6 Hydrochloride is a deuterium-labeled Aliskiren. Aliskiren hemifumarate is a direct and orally active renin inhibitor (IC50: 1.5 nM).
T19187 Aliskiren D6 hemifumarate CGP 60536 D6 hemifumarate,SPP 100 D6 hemifumarate,CGP60536B D6 hemifumarate RAAS
Aliskiren (CGP 60536) D6 hemifumarate is a deuterium-labeled Aliskiren hemifumarate. Aliskiren hemifumarate is a direct and orally active renin inhibitor (IC50: 1.5 nM).
T0909L Nalidixic acid sodium salt Baktogram,Sodium nalidixate Topoisomerase , Antibacterial , Antibiotic
Nalidixic acid sodium salt (Baktogram) is an antimicrobial agent with a limited bacteriocidal spectrum.
T23859 CaspPro C-2,C 2,Casp-Pro,Casp Pro,C2
CaspPro is a selective activator of caspase 8 that acts by potentiating TRAIL-induced cell death.
T81112 SPPHPSPAFSPAFDNLYYWDQ
SPPHPSPAFSPAFDNLYYWDQ is a multi-epitope class II rat HER2/neu peptide applicable in the investigation of class II HER2-DC1 vaccine studies [1].
T76367 VSPPLTLGQLLS
VSPPLTLGQLLS, also known as peptide P3, is a small peptide that serves as an inhibitor of FGFR3, effectively suppressing FGFR3 phosphorylation. It hinders 9-cisRA-induced tracheal lymphangiogenesis and impedes lymphatic ...
T78442 TSPP tetrasodium
TSPP tetrasodium, a photosensitizer, has demonstrated significant efficacy in the in vivo regression of cancer and microbial infections (Ex: 413 nm, Em: 640 nm) [1][2].
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