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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T1676 | Rosuvastatin | ZD 4522 | Potassium Channel , HMG-CoA Reductase , Autophagy |
Rosuvastatin (ZD 4522) is an antilipemic agent that competitively inhibits hydroxymethyl-glutaryl-coenzyme A (HMG-CoA) reductase. HMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting... | |||
T1510 | Rosuvastatin calcium | ZD 4522 Calcium,ZD4522,Rosuvastatin hemicalcium | Potassium Channel , HMG-CoA Reductase , Autophagy |
Rosuvastatin calcium (ZD4522) , a selective and competitive inhibitor of hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, has antilipidemic activity. | |||
T81257 | Rosuvastatin zinc salt | Rosuvastatin zinc | |
Rosuvastatin zinc salt (Rosuvastatin zinc), a zinc-infused variant of Rosuvastatin, functions as an HMG-CoA reductase inhibitor, utilized primarily in atherosclerosis research [1]. | |||
T69178 | Rosuvastatin lactone | ||
Rosuvastatin lactone is the lactone form of the HMG-CoA reductase inhibitor rosuvastatin. It is found in vivo following rosuvastatin administration. Rosuvastatin lactone is an inhibitor of the cytochrome P450 (CYP) isofo... | |||
T19551 | Rosuvastatin D6 Calcium | Others | |
Rosuvastatin D6 Calcium is deuterium labeled Rosuvastatin, which is a competitive HMG-CoA reductase inhibitor(IC50 of 11 nM). | |||
T12757 | Rosuvastatin D3 Sodium | Others | |
Rosuvastatin D3 Sodium is deuterium labeled Rosuvastatin, which is a competitive HMG-CoA reductase inhibitor(IC50 of 11 nM). | |||
T10131 | (3S,5R)-Rosuvastatin | Others | |
(3S,5R)-Rosuvastatin is the (3R,5R)-enantiomer of Rosuvastatin. Rosuvastatin is a competitive HMG-CoA reductase inhibitor (IC50: 11 nM). | |||
T10126 | (3R,5R)-Rosuvastatin | Others | |
(3R,5R)-Rosuvastatin is the (3R,5R)-enantiomer of Rosuvastatin. Rosuvastatin is a competitive HMG-CoA reductase inhibitor (IC50: 11 nM). | |||
T12759 | Rosuvastatin D6 Sodium | Others | |
Rosuvastatin D6 Sodium is deuterium labeled Rosuvastatin, which is a competitive HMG-CoA reductase inhibitor(IC50 of 11 nM). | |||
T35718 | N-desmethyl Rosuvastatin (sodium salt hydrate) | ||
N-desmethyl Rosuvastatin is an active metabolite of the HMG-CoA reductase inhibitor rosuvastatin .1,2N-desmethyl Rosuvastatin is formed when rosuvastatin undergoes demethylation, primarily by the cytochrome P450 (CYP) is... | |||
T19132 | (3R,5R)-Rosuvastatin Lactone | Others | |
(3R,5R)-Rosuvastatin Lactone is an isomer of Rosuvastatin Lactone. | |||
T63430 | Rosuvastatin Sodium | ||
Rosuvastatin Sodium is a competitive HMG-CoA reductase (HMGCR) inhibitor (IC50: 11 nM) that effectively blocks hERG currents (IC50: 195 nM). Rosuvastatin Sodium reduces the expression of mature hERG and inhibits the inte... |