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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6644 | Rolipram | SB 95952,ZK 62711,(R,S)-Rolipram | HIV Protease , Antibacterial , PDE |
Rolipram (SB 95952) is a phosphodiesterase 4 inhibitor with antidepressant properties. | |||
T6649 | (S)-(+)-Rolipram | (S)-Rolipram,(+)-Rolipram,S- (+)-Rolipram | Apoptosis , PDE |
(S)-(+)-Rolipram ((+)-Rolipram) inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM, has anti-inflammatory and anti-depressant activity in the central nervous system, less potent than its R enantiomer. | |||
T13448 | (R)-(-)-Rolipram | (R)-Rolipram,(-)-Rolipram | DNA-PK , Others |
(R)-(-)-Rolipram ((-)-Rolipram) is an R-enantiomer of Rolipram which is a PDE4 inhibitor. | |||
T71421 | Bemoradan | ||
Bemoradan is an inhibitor of the rolipram-insensitive cyclic AMP phosphodiesterase from canine heart tissue | |||
T60934 | PDE4-IN-9 | ||
PDE4-IN-9 (Compound 5j) is a potent PDE4 inhibitor. In vitro enzyme assay, the IC 50 value of PDE4-IN-9 against PDE4 is 1.4 μM which is lower than 2.0 μM of parent rolipram. PDE4-IN-9 also shows good in vivo activity in ... |