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Search Results for " rr1 "

Targets

10

Compounds

2

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T77549 Nurr1 agonist 2 Others
Nurr1 agonist 2 is a Nurr1 agonist with an EC50 value of 0.07 μM. Nurr1 agonist 2 increases the mRNA expression of the Nurr1-regulated genes tyrosine hydroxylase (TH) and vesicular amino acid transporter 2 (VMAT2). Nurr1...
T83894 4A7C-301-Nurr1 Agonist 4A7C-301-Nuclear Receptor-Related 1
The compound 4A7C-301-Nurr1 agonist is a specific agonist for the nuclear receptor-related 1 (Nurr1). By binding to the Nurr1 ligand-binding domain with an IC50 value of 48.22 nM, it enhances the transcriptional activity...
T78088 Nurr1 agonist 4 Others
Nurr1 agonist 4 (compound 8) serves as a potent Nurr1 agonist, exhibiting an EC50 value of 2.1 μM [1].
T81634 Nurr1 agonist 6
Compound 13, a Nurr1 agonist, exhibits a dissociation constant (Kd) of 1.5 μM and an effective concentration for 50% response (EC50) of 3 μM [1].
T60443 Nurr1 agonist 1
Nurr1 agonist 1 is an inverse agonist tool for the neuroprotective transcription factor Nurr1 which is an appealing target to treat neurodegenerative diseases.
T80771 WRR139
WRR139, a peptide vinyl sulfone, plays a role in disease processes including inflammation and cancer, and acts as an inhibitor of cytosolic enzyme N-glycanase 1 (NGLY1) and Nrf1. Moreover, WRR139 amplifies the cytotoxic ...
T81633 Nurr1 agonist 7
Nurr1 agonist 7 (compound 110) is an agonist targeting the Nurr1 receptor and exhibits an EC50 of 0.12 μM [1].
T81632 Nurr1 agonist 8
Compound 111 (Nurr1 agonist 8) is a Nurr1 agonist exhibiting an EC50 value of 0.09 μM [1].
T78049 Nurr1 inverse agonist-1 Others
Nurr1 Inverse Agonist-1 is an inverse agonist for the neuroprotective transcription factor Nurr1, serving as a research tool.
T81635 Nurr1 agonist 5
Compound 5o, a Nurr1 agonist, exhibits neuroprotective properties as a transcription factor Nurr1 agonist, possessing a dissociation constant (Kd) of 0.5 μM and a half-maximal effective concentration (EC50) of 3 μM [1].

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-03287 RRM1 Protein, Human, Recombinant (His & GST) Human Baculovirus Insect Cells
RRM1 is a subunit of ribonucleoside-diphosphate reductase which is constituted by two subunits. Ribonucleoside-diphosphate reductase is an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesi...
TMPH-02142 ERR1 Protein, Human, Recombinant (GST) Human E. coli
Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an importan...
TargetMol