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Cat No. | Product Name | Synonyms | Targets |
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T77549 | Nurr1 agonist 2 | Others | |
Nurr1 agonist 2 is a Nurr1 agonist with an EC50 value of 0.07 μM. Nurr1 agonist 2 increases the mRNA expression of the Nurr1-regulated genes tyrosine hydroxylase (TH) and vesicular amino acid transporter 2 (VMAT2). Nurr1... | |||
T83894 | 4A7C-301-Nurr1 Agonist | 4A7C-301-Nuclear Receptor-Related 1 | |
The compound 4A7C-301-Nurr1 agonist is a specific agonist for the nuclear receptor-related 1 (Nurr1). By binding to the Nurr1 ligand-binding domain with an IC50 value of 48.22 nM, it enhances the transcriptional activity... | |||
T78088 | Nurr1 agonist 4 | Others | |
Nurr1 agonist 4 (compound 8) serves as a potent Nurr1 agonist, exhibiting an EC50 value of 2.1 μM [1]. | |||
T81634 | Nurr1 agonist 6 | ||
Compound 13, a Nurr1 agonist, exhibits a dissociation constant (Kd) of 1.5 μM and an effective concentration for 50% response (EC50) of 3 μM [1]. | |||
T60443 | Nurr1 agonist 1 | ||
Nurr1 agonist 1 is an inverse agonist tool for the neuroprotective transcription factor Nurr1 which is an appealing target to treat neurodegenerative diseases. | |||
T80771 | WRR139 | ||
WRR139, a peptide vinyl sulfone, plays a role in disease processes including inflammation and cancer, and acts as an inhibitor of cytosolic enzyme N-glycanase 1 (NGLY1) and Nrf1. Moreover, WRR139 amplifies the cytotoxic ... | |||
T81633 | Nurr1 agonist 7 | ||
Nurr1 agonist 7 (compound 110) is an agonist targeting the Nurr1 receptor and exhibits an EC50 of 0.12 μM [1]. | |||
T81632 | Nurr1 agonist 8 | ||
Compound 111 (Nurr1 agonist 8) is a Nurr1 agonist exhibiting an EC50 value of 0.09 μM [1]. | |||
T78049 | Nurr1 inverse agonist-1 | Others | |
Nurr1 Inverse Agonist-1 is an inverse agonist for the neuroprotective transcription factor Nurr1, serving as a research tool. | |||
T81635 | Nurr1 agonist 5 | ||
Compound 5o, a Nurr1 agonist, exhibits neuroprotective properties as a transcription factor Nurr1 agonist, possessing a dissociation constant (Kd) of 0.5 μM and a half-maximal effective concentration (EC50) of 3 μM [1]. |
Cat No. | Product Name | Species | Expression System |
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TMPY-03287 | RRM1 Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
RRM1 is a subunit of ribonucleoside-diphosphate reductase which is constituted by two subunits. Ribonucleoside-diphosphate reductase is an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesi... | |||
TMPH-02142 | ERR1 Protein, Human, Recombinant (GST) | Human | E. coli |
Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an importan... |