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Search Results for " quizartinib "

4

Compounds

Cat No. Product Name Synonyms Targets
T2066 Quizartinib AC220 Apoptosis , FLT , Autophagy , Ligands for Target Protein for PROTAC
Quizartinib (AC220) is an inhibitor of FLT3 (Kd: 1.6 nM) and demonstrates high selectivity for FLT3 when tested against a panel of 227 additional kinases.
T39818 Desmorpholinyl Quizartinib-PEG2-COOH Desmorpholinyl Quizartinib-PEG2-COOH
Desmorpholinyl Quizartinib-PEG2-COOH is a compound featuring an FLT-3 ligand and a PEG-based PROTAC linker. It is employed in the synthesis of PROTAC FLT-3 degrader 1, which serves as a degrader for the FLT-3 internal ta...
T71400 Quizartinib HCl
Quizartinib, also know as AC220 and AC010220, is an orally available FLT3 / STK1 inhibitor with potential antineoplastic activity. Class III receptor tyrosine kinase inhibitor AC220 selectively inhibits class III recept...
T71399 Plogosertib CYC140
Plogosertib (CYC140), a selective and potent orally active ATP-competitive PLK1 inhibitor (IC 50: 3 nM), functions as an anticancer agent with antiproliferative effects. It is utilized in the research of various tumors s...
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