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Search Results for " pdp "

Targets

40

Compounds

1

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T28353 PDP-EA FAAH
PDP-EA is an activator of fatty acid amide hydrolase(FAAH) and enhances the amidohydrolase activity of FAAH.
T18531 PDP-Pfp Others
PDP-Pfp is a reducible ADC linker primarily utilized for targeting agents aimed at the extracellular loop 1 (ECL1) of TM4SF1, a member of the transmembrane 4 L6 family, as supported by reference [1].
T18530 PDP-C1-Ph-Val-Cit Others
PDP-C1-Ph-Val-Cit is a cleavable ADC linker used for antibody-drug conjugates (ADCs).
T74302 DSPE-PEG-PDP
DSPE-PEG-PDP, a phospholipid-polyethylene glycol (PEG) conjugate, is utilized in drug delivery applications [1].
T6741 SPDP SPDP Crosslinker Others
SPDP is a short-chain crosslinker, which is used for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls. SPDP could ...
TP2036L DPDPE TFA (88373-73-3 free base) DPDPE TFA Opioid Receptor
DPDPE TFA is selective δ-opioid receptor agonist peptide. Inhibits electrically stimulated contraction of mouse vas deferens in vitro (EC50 = 5.2 nM), and is antinociceptive in vivo.
T19955 Biotin-HPDP Pyridyldisulfide-biotin,Pyridyldithiol-biotin Others
Biotin-HPDP (Pyridyldithiol-biotin) is a sulfhydryl reactive biotinylation reagent.
T17834 DM4-SPDP Others
DM4-SPDP, a drug-linker conjugate, integrates the antitubulin agent DM4 with the linker SMCC, facilitating the creation of antibody drug conjugates[1]. Additionally, SPDP serves as a short-chain crosslinker enabling amin...
T18715 SPDP-PEG7-acid Others
SPDP-PEG7-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system wi...
T18714 SPDP-PEG5-acid Others
SPDP-PEG5-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system wi...
T16918 SPDP-PEG6-NHS ester Others
SPDP-PEG6-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome syst...
T18712 SPDP-PEG24-NHS ester Others
SPDP-PEG24-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome sys...
T35493 (±)10(11)-EpDPA
Cytochrome P450 metabolism of polyunsaturated fatty acids produces numerous bioactive epoxide regioisomers. (±)10(11)-EpDPA is a docosahexaenoic acid epoxygenase metabolite, derived via epoxidation of the 10,11-double bo...
T37235 (±)16(17)-EpDPA (±)16,17-EpDPE,(±)16,17 EDP,(±)16,17-epoxy Docosapentaenoic Acid,(±)16,17-epoxy DPA,(±)16(17)-EpDPA
EDHF (endothelium-derived hyperpolarizing factor) is an unidentified mediator released from vascular endothelial cells in response to acetylcholine and bradykinin which is distinct from the NOS- (nitric oxide) and COX-de...
T18535 PEG4-SPDP Others
PEG4-SPDP is a cleavable ADC linker used for the antibody-drug conjugates (ADCs).
T18733 Sulfo-SPDP-C6-NHS sodium Others
Sulfo-SPDP-C6-NHS sodium is a sodium salt form of a cleavable ADC linker employed in the synthesis of antibody-drug conjugates (ADCs)[1].
T18709 SPDP-PEG12-acid Others
SPDP-PEG12-acid is a cleavable 12-unit polyethylene glycol (PEG) linker utilized for the synthesis of antibody-drug conjugates (ADCs)[1].
TP2036 DPDPE Opioid Receptor
DPDPE is selective δ-opioid receptor agonist peptide. Inhibits electrically stimulated contraction of mouse vas deferens in vitro (EC50 = 5.2 nM), and is antinociceptive in vivo.
T18725 Sulfo-LC-SPDP Others
Sulfo-LC-SPDP is a heterobifunctional crosslinker characterized by its thiol-cleavable and membrane impermeable properties.
T18711 SPDP-PEG24-acid Others
SPDP-PEG24-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system w...
T18716 SPDP-PEG9-acid Others
SPDP-PEG9-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system wi...
T38597 SPDP-sulfo
SPDP-sulfo is a cleavable linker vital in ADC synthesis. SPDP-sulfo joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing AD...
T16917 SPDP-PEG4-NHS ester Others
SPDP-PEG4-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome syst...
T16916 SPDP-PEG4-acid Others
SPDP-PEG4-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system wi...
T15724 LC-PEG8-SPDP Others
LC-PEG8-SPDP is a cleavable ADC linker used for the antibody-drug conjugates (ADCs)[1].
T18708 SPDP-C6-Gly-Leu-NHS ester Others
SPDP-C6-Gly-Leu-NHS ester is a cleavable linker employed in the synthesis of antibody-drug conjugates (ADCs)[1].
T16915 SPDP-C6-NHS ester Others
SPDP-C6-NHS ester is an alkyl/ether-based linker utilized in the synthesis of PROTACs[1].
T35496 (±)13(14)-EpDPA
Cytochrome P450 metabolism of polyunsaturated fatty acids produces numerous bioactive epoxide regioisomers. (±)13(14)-EpDPA is a docosahexaenoic acid epoxygenase metabolite, derived via epoxidation of the 13,14-double bo...
T35497 (±)7(8)-EpDPA
Docosahexaenoic acid is the most abundant ω-3 fatty acid in neural tissues, especially in the brain and retina. (±)7(8)-EpDPA is an epoxide derivative of DHA that is generated by the action of cytochrome P450 epoxygenase...
T33904 PDPH Crosslinker PDPH Cross linker,SPDP Hydrazide,PDPH Cross-linker
PDPH crosslinker(SPDP Hydrazide) is a lytic heterobisfunctional protein crosslinker.
T18525 PC SPDP-NHS carbonate ester Others
PC SPDP-NHS carbonate ester is a cleavable linker compound utilized in the synthesis of antibody-drug conjugates (ADCs)[1].
T60528 PDPOB
PDPOB is a phenyl carboxylic acid derivative with the potential to be used in the study of cerebral ischemia. PDPOB is shown to be protective against OGD/R-evoked multi-aspect neuronal deterioration in SH-SY5Y cells, as ...
T18710 SPDP-PEG12-NHS ester Others
SPDP-PEG12-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome sys...
T36218 19R(20S)-EpDPA
19R(20S)-EpDPA is an oxylipin and a metabolite of docosahexaenoic acid .1,2It is formed from DHA by various cytochrome P450 (CYP) isoforms in a stereoselective manner.219R(20S)-EpDPA (30 nM) prevents calcium-induced incr...
T77286 DSPE-SPDP
DSPE-SPDP, a phospholipid molecule, possesses the ability to form lipid bilayers in water, making it valuable for biochemical research [1].
T18713 SPDP-PEG36-NHS ester Others
SPDP-PEG36-NHS ester is a PEG ADC linker consisting of 36 units, characterized by cleavability. It plays a crucial role in the synthesis of antibody-drug conjugates (ADCs)[1].
T37238 (±)19(20)-EpDPA
EDHF (endothelium-derived hyperpolarizing factor) is an unidentified mediator released from vascular endothelial cells in response to acetylcholine and bradykinin which is distinct from the NOS- (nitric oxide) and COX-de...
T37241 (±)4(5)-EpDPA methyl ester
(±)4(5)-EpDPA methyl ester is a derivative of (±)4(5)-EpDPA which is stable enough to ship and handle routinely. The active free acid can be regenerated from the methyl ester by careful base hydrolysis. (±)4(5)EpDPA is a...
T14908 CCT367766 PROTACs
CCT367766 is a potent, PROTAC-based, third-generation, iso-functional pirin-targeted protein degradation probe (PDP) that depletes pirin expression at low concentrations.CCT367766 has an IC50 value of 490 nM for the CRBN...
T77915 CCT367766 formic PROTACs
CCT367766 formic is a potent third-generation heterobifunctional Cereblon-based protein degradation probe (PDP, or PROTAC) that selectively targets pirin for degradation, effectively diminishing its protein expression at...

Compounds

PDP-EA
T28353
Synonym:
Target: FAAH
PDP-Pfp
T18531
Synonym:
Target: Others
PDP-C1-Ph-Val-Cit
T18530
Synonym:
Target: Others
DSPE-PEG-PDP
T74302
Synonym:
Target:
SPDP
T6741
Synonym: SPDP Crosslinker
Target: Others
DPDPE TFA (88373-73-3 free base)
TP2036L
Synonym: DPDPE TFA
Target: Opioid Receptor
Biotin-HPDP
T19955
Synonym: Pyridyldisulfide-biotin,Pyridyldithiol-biotin
Target: Others
DM4-SPDP
T17834
Synonym:
Target: Others
SPDP-PEG7-acid
T18715
Synonym:
Target: Others
SPDP-PEG5-acid
T18714
Synonym:
Target: Others
SPDP-PEG6-NHS ester
T16918
Synonym:
Target: Others
SPDP-PEG24-NHS ester
T18712
Synonym:
Target: Others
(±)10(11)-EpDPA
T35493
Synonym:
Target:
(±)16(17)-EpDPA
T37235
Synonym: (±)16,17-EpDPE,(±)16,17 EDP,(±)16,17-epoxy Docosapentaenoic Acid,(±)16,17-epoxy DPA,(±)16(17)-EpDPA
Target:
PEG4-SPDP
T18535
Synonym:
Target: Others
Sulfo-SPDP-C6-NHS sodium
T18733
Synonym:
Target: Others
SPDP-PEG12-acid
T18709
Synonym:
Target: Others
DPDPE
TP2036
Synonym:
Target: Opioid Receptor
Sulfo-LC-SPDP
T18725
Synonym:
Target: Others
SPDP-PEG24-acid
T18711
Synonym:
Target: Others
SPDP-PEG9-acid
T18716
Synonym:
Target: Others
SPDP-sulfo
T38597
Synonym:
Target:
SPDP-PEG4-NHS ester
T16917
Synonym:
Target: Others
SPDP-PEG4-acid
T16916
Synonym:
Target: Others
LC-PEG8-SPDP
T15724
Synonym:
Target: Others
SPDP-C6-Gly-Leu-NHS ester
T18708
Synonym:
Target: Others
SPDP-C6-NHS ester
T16915
Synonym:
Target: Others
(±)13(14)-EpDPA
T35496
Synonym:
Target:
(±)7(8)-EpDPA
T35497
Synonym:
Target:
PDPH Crosslinker
T33904
Synonym: PDPH Cross linker,SPDP Hydrazide,PDPH Cross-linker
Target:
PC SPDP-NHS carbonate ester
T18525
Synonym:
Target: Others
PDPOB
T60528
Synonym:
Target:
SPDP-PEG12-NHS ester
T18710
Synonym:
Target: Others
19R(20S)-EpDPA
T36218
Synonym:
Target:
DSPE-SPDP
T77286
Synonym:
Target:
SPDP-PEG36-NHS ester
T18713
Synonym:
Target: Others
(±)19(20)-EpDPA
T37238
Synonym:
Target:
(±)4(5)-EpDPA methyl ester
T37241
Synonym:
Target:
CCT367766
T14908
Synonym:
Target: PROTACs
CCT367766 formic
T77915
Synonym:
Target: PROTACs

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-00714 CD5L Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
CD5L Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38 kDa and the accession number is Q9QWK4.
TargetMol