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Search Results for " pim-in-2 "

5

Compounds

Cat No. Product Name Synonyms Targets
T81460 PIM-IN-2 Pim
PIM-IN-2 (Pim-2) is a potent inhibitor of Pim kinases, demonstrating an inhibition concentration half-maximal (IC50) value of 25 nM . It exhibits antiapoptotic properties conducive to cell survival and has been found to ...
T9229 Pim-1/2 kinase inhibitor 1 Pim
Pim-1/2 Kinase Inhibitor 1, an orally active inhibitor, impedes the action of Pim kinases by preventing their ability to phosphorylate peptides. It particularly inhibits the phosphorylation of 4E-BP1 and p27 Kip1 by Pim ...
T3078 SGI-1776 SGI-1776 free base,Pim-Kinase Inhibitor IX Apoptosis , FLT , Pim , Autophagy
SGI-1776 (Pim-Kinase Inhibitor IX) has been used in trials studying the treatment of Prostate Cancer, Non-Hodgkins Lymphoma, and Relapsed/Refractory Leukemias.
T9583 HJ-PI01 N-Acetylphenoxazine,10-acetylphenoxazine Pim
HJ-PI01 (HJ-PI01) is a Pim-2 inhibitor. HJ-PI01 (HJ-PI01) induces apoptosis and autophagic cell death in triple-negative human breast cancer.
T68341 HS56
HS56 is an ATP-competitive dual Pim/DAPK3 inhibitor, displaying K i values of 0.26 μM for DAPK3, 0.208 μM for Pim-3, 2.94 μM for Pim-1, and >100 μM for Pim-2. This compound effectively inhibits LC20 phosphorylation and s...
TargetMol