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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T62392 | PI3K-IN-34 | ||
PI3K-IN-34 (Compound 6g) is a highly selective inhibitor of PI3K that acts on PI3K-α (IC50: 11.73 μM), PI3K-β (IC50: 6.09 μM) and PI3K-δ (IC50: 11.18 μM). PI3K-IN-34 can be used to study leukaemia. | |||
T7015 | Vps34-IN-1 | VPS34-IN1 | PI3K , Autophagy |
Vps34-IN-1 (VPS34-IN1) is a potent and highly selective Vps34 inhibitor with IC50 of 25 nM in vitro, which does not significantly inhibit the isoforms of class I as well as class II PI3Ks. | |||
T15789 | LTURM34 | DNA-PK , PI3K , PI4K | |
LTURM34 is an inhibitor of DNA-PK with IC50 of 34 nM. LTURM34 displays effective antiproliferative activity in a wide range of tumor cell lines. LTURM34 shows 170-fold selectivity for DNA-PK over PI3K . |