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Search Results for " pi3k-in-27 "

5

Compounds

Cat No. Product Name Synonyms Targets
T64052 PI3K-IN-27
PI3K-IN-27 is a potent inhibitor of PI3K, a large family of lipid signalling kinases that play a key role in cellular processes such as cell growth, differentiation, migration and apoptosis. PI3K-IN-27 has shown research...
T1916 Apitolisib RG 7422,GNE 390,GDC-0980 Apoptosis , PI3K , mTOR
Apitolisib (RG 7422), an effective, class I PI3K inhibitor for PI3Kα(IC50=5 nM), PI3Kβ(IC50=27 nM), PI3Kδ(IC50=7 nM), PI3Kγ (IC50=14 nM), is used in trials study of solid cancers, breast cancer, prostate cancer, renal ce...
T78853 PI3K-IN-47 PI3K
PI3K-IN-47 (Compound 27) is a potent bivalent inhibitor targeting the phosphoinositide 3-kinases (PI3K) family, exhibiting inhibitory concentration (IC50) values of 0.44 nM for PI3Kα, and 7.18 nM, 13.92 nM, 22.83 nM for ...
T61656 Antitumor agent-53
Antitumor agent-53 is a potent compound that effectively inhibits tumor growth. It achieves this by inducing cell cycle arrest at the G2/M phase and promoting apoptosis in HGC-27 cells through the inhibition of the PI3K/...
T35491 3,5-dimethyl PIT-1
PtdIns-(3,4,5)-P3 (PIP3) serves as an anchor for the binding of signal transduction proteins bearing pleckstrin homology (PH) domains such as phosphatidylinositol 3-kinase (PI3K) or PTEN. Protein binding to PIP3 is impor...
TargetMol