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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6143 | PI-103 | PI103,PI 103 | Apoptosis , DNA-PK , PI3K , mTOR , Autophagy |
PI-103 is a potent, cell-permeable, ATP-competitive inhibitor of PI3K family members (IC50s: 2/3/3/15/30/23 nM for p110α/β/δ/γ, mTOR, and DNA-PK). | |||
T6143L | PI-103 Hydrochloride | ||
PI-103 Hydrochloride is a potent dual inhibitor of PI3K and mTOR, demonstrating inhibitory IC50 values of 8 nM for p110α, 88 nM for p110β, 48 nM for p110δ, 150 nM for p110γ, 20 nM for mTORC1, and 83 nM for mTORC2, respec... | |||
T63527 | RIDR-PI-103 | ||
RIDR-PI-103 is a reactive oxygen species (ROS)-induced drug release prodrug containing an autocyclized portion linked to a pan-PI3K inhibitor (PI-103). In MDA-MB-361 and MDA-MB-231 cells, Doxorubicin and RIDR-PI-103 exhi... | |||
T3190 | PIK-inhibitors | MDK34597 | PI3K |
PIK-inhibitors (MDK34597) is a pan PI3K inhibitors, an analog of PI-103. |