Home Tools

Log in

Search Result

Search Results for " pd-l1-in-3 "

11

Compounds

Cat No.	Product Name	Synonyms	Targets
T79314	PD-L1-IN-3		PD-1/PD-L1
	PD-L1-IN-3 (Compound 4a) functions as an inhibitor targeting the PD-1/PD-L1 axis, with an IC50 value of 4.97nM for PD-L1 inhibition and an EC50 value of 2.70 μM for Jurkat T cell modulation. It antagonizes the PD-1/PD-L1...		PD-1/PD-L1
TP1463	PD-1/PD-L1-IN 3 TFA (1629654-95-0 free base)	PD-1/PD-L1-IN 3 TFA
	PD-1/PD-L1-IN 3 TFA inhibits the binding of human PD-1 to PD-Ll with an IC50 of 9 nM.
T73642	PD-1/PD-L1-IN 3 TFA
	PD-1/PD-L1-IN 3 TFA, a macrocyclic peptide, serves as a potent and selective inhibitor of PD-1/PD-L1 interaction. This compound disrupts PD-L1's binding with PD-1 and CD80 by directly binding to PD-L1, exhibiting IC50 va...
T79740	CYP51/PD-L1-IN-3
	CYP51/PD-L1-IN-3 (compound L21), a quinazoline with antifungal properties, serves as a dual inhibitor targeting CYP51 (IC50: 0.205 μM) and PD-L1 (IC50: 0.039 μM). This compound promotes early fungal apoptosis within the ...
T37535	Camrelizumab	SHR-1210
	Camrelizumab (SHR-1210) is a human IgG4-κ monoclonal antibody with high affinity and directed against PD-1.Camrelizumab binds PD-1 with a binding affinity of up to 3 nM and is inhibitory to PD-1/PD-L1 with an IC50 of 0.7...
T6S0071	Fraxinellone		HIF/HIF Prolyl-Hydroxylase , STAT , PD-1/PD-L1
	1. Fraxinellone significantly reduced weight loss and diarrhea in mice and alleviated the macroscopic and microscopic signs of the disease. 2. Fraxinellone exhibited a variety of insecticidal activities including feeding...		HIF/HIF Prolyl-Hydroxylase , STAT , PD-1/PD-L1
T72691	PD-1/PD-L1-IN-28
	PD-1/PD-L1-IN-28, an inhibitor of the PD-1/PD-L1 signaling pathway (IC 50 = 0.744 µM), demonstrates promising research potential in tumor immunity. This immune checkpoint inhibitor effectively blocks the interaction with...
T79634	LYP-IN-3		Phosphatase
	LYP-IN-3 (compound D34) is a selective Lymphoid-tyrosine phosphatase (LYP) inhibitor (Ki=0.93 μM) that modulates the T-cell receptor (TCR) signaling pathway during tumor progression. It promotes T-cell activation, hinder...		Phosphatase
T36047	LH1307
	LH1307 is an inhibitor of the interaction between programmed cell death 1 (PD-1) and its ligand PD-L1 that has an IC50 value of 3 nM in a homologous time-resolved fluorescence (HTRF) assay.1 It increases the activation o...
T82414	Favezelimab	MK-4280
	Favezelimab (MK-4280) is a humanized anti-LAG-3 monoclonal antibody that inhibits the LAG-3/MHC class II interaction and shows potential for use in colorectal cancer (CRC) research, particularly when combined with the PD...
T76997	Socazolimab
	Socazolimab (ZKAB001), an anti-PD-L1 monoclonal antibody, demonstrates enduring safety and efficacy in treating recurrent or metastatic cervical cancer. Additionally, it shows promise for treating small cell lung cancer,...

Compounds

Target: PD-1/PD-L1

PD-1/PD-L1-IN 3 TFA (1629654-95-0 free base)

Synonym: PD-1/PD-L1-IN 3 TFA

PD-1/PD-L1-IN 3 TFA

CYP51/PD-L1-IN-3

Synonym: SHR-1210

Target: HIF/HIF Prolyl-Hydroxylase, STAT, PD-1/PD-L1

PD-1/PD-L1-IN-28

Target: Phosphatase

Synonym: MK-4280

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.

TargetMol

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved.

TargetMol