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Search Results for " pc1 "

Targets

9

Compounds

13

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T7495 Hexa-D-arginine Others
Hexa-D-arginine is an inhibitor of furin,blocks the activation of Pseudomonas aeruginosa exotoxin A in vivo.
T29112 VPC171 VPC 171,VPC-171 Adenosine Receptor
VPC171 is a novel adenosine A1 receptor positive allosteric modulator (PAM).
T83974 OPC18750 HCl PDE
OPC18750 HCl is a potential phosphodiesterase inhibitor with positive inotropic effects that can be used to study asthma, cancer, diabetes, and psychiatric disorders.
T61274 PC190723
PC190723 (Compound 2), an inhibitor of the FtsZ bacterial cell division protein, demonstrates potent efficacy with an IC50 value of 55 ng/ml. Additionally, it showcases notable anti-staphylococcal activity, characterized...
T29109 VPC12249 VPC-12249,VPC 12249
VPC12249, a lysophosphatidic acid receptor type 1 (LPA1) antagonist, plays a functional role in osteoclast differentiation and bone resorption activity.
T24599 PC170942 Sodium PC170942 Sodium salt
PC170942 Sodium is a water-soluble bacterial cytokinesis inhibitor that acts by inhibiting FtsZ.
TP1160 Hexa-D-arginine TFA Furin Inhibitor II TFA
Hexa-D-arginine TFA (Furin Inhibitor II TFA) is an inhibitor of furin (Ki values are 0.106, 0.58 and 13.2 μM for furin, PACE4 and PC1 respectively).
TP2038 Decanoyl-RVKR-CMK
Subtilisin/Kex2p-like proprotein convertase inhibitor; blocks activity of all seven convertases (PC1, PC2, PC4, PACE4, PC5, PC7 and furin). Abolishes proET-1 processing in endothelial cells; inhibits regulated secretion ...
T78224 Histatin-3
Histatin-3, a 32-amino-acid peptide, exhibits potent antimicrobial activities and serves as a substrate for proprotein convertase 1 (PC1), where it is primarily cleaved at a site carboxy-terminal to Arg25 (HRGYR↓SN). Add...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-01635 PCSK1 Protein, Human, Recombinant (His) Human HEK293
Neuroendocrine convertase 1, also known as Prohormone convertase 1, Proprotein convertase 1, PCSK1 and NEC1, is an enzyme which belongs to the peptidase S8 family and Furin subfamily. PCSK1 is an enzyme that performs the...
TMPK-00781 ENPP1 Protein, Mouse, Recombinant (His) Mouse HEK293
Ectonucleotide pyrophosphatase/phosphodiesterase (ENPP)-1 is a membrane-bound protein that catalyzes the hydrolysis of extracellular nucleoside triphosphates to monophosphate and extracellular inorganic pyrophosphate (eP...
TMPK-00854 ENPP1 Protein, Human, Recombinant (C-His) Human HEK293
Ectonucleotide pyrophosphatase/phosphodiesterase (ENPP)-1 is a membrane-bound protein that catalyzes the hydrolysis of extracellular nucleoside triphosphates to monophosphate and extracellular inorganic pyrophosphate (eP...
TMPK-00852 ENPP1 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
Ectonucleotide pyrophosphatase/phosphodiesterase (ENPP)-1 is a membrane-bound protein that catalyzes the hydrolysis of extracellular nucleoside triphosphates to monophosphate and extracellular inorganic pyrophosphate (eP...
TMPK-00853 ENPP1 Protein, Human, Recombinant (N-His) Human HEK293
Ectonucleotide pyrophosphatase/phosphodiesterase (ENPP)-1 is a membrane-bound protein that catalyzes the hydrolysis of extracellular nucleoside triphosphates to monophosphate and extracellular inorganic pyrophosphate (eP...
TMPH-01885 PABPC1 Protein, Human, Recombinant (His & SUMO) Human E. coli
Binds the poly(A) tail of mRNA, including that of its own transcript, and regulates processes of mRNA metabolism such as pre-mRNA splicing and mRNA stability. Its function in translational initiation regulation can eithe...
TMPH-00093 GAPC1, cytosolic Protein, Arabidopsis thaliana, Recombinant (His & Myc) Arabidopsis thaliana E. coli
Key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Essential for the maintenance of cellular ATP levels and carboh...
TMPH-02905 TRPC1 Protein, Mouse, Recombinant (His) Mouse in vitro E. coli expression system
Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled recep...
TMPY-00131 Niemann Pick C1/NPC1 Protein, Human, Recombinant (His & FLAG) Human HEK293
Niemann-Pick C1 (NPC1), a host receptor involved in the envelope glycoprotein (GP)-mediated entry of filoviruses into cells, is believed to be a major determinant of cell susceptibility to filovirus infection. Niemann-Pi...
TMPH-01407 Glypican 1/GPC1 Protein, Human, Recombinant (GST & His & Myc) Human E. coli
Glypican 1/GPC1 Protein, Human, Recombinant (GST & His & Myc) is expressed in E. coli.
TMPH-00931 ANAPC15 Protein, Human, Recombinant (GST) Human E. coli
ANAPC15 Protein, Human, Recombinant (GST) is expressed in E. coli.
TMPJ-00330 GPC1 Protein, Human, Recombinant (His) Human Human Cells
The Glypicans are a small multigene family of GPI-linked proteoglycans that play a key role in growth factor signaling. Human Glypican 1 (GPC1) is synthesized as a 558 amino acid (aa) preproprecursor that contains a 23 a...
TMPJ-01368 GPC1 Protein, Mouse, Recombinant (His) Mouse Human Cells
Glypican-1 is a cell membrane protein and belongs to the glypican family. The protein may act as a catalyst in increasing the rate of conversion of prion protein PRPN(C) to PRNP(Sc) via associating (via the heparan sulfa...
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