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Search Results for " pbp2 "

8

Compounds

Cat No. Product Name Synonyms Targets
T33894 PBP2 PBP-2,PBP 2
PBP2 is a selective inducer of G-quadruplex structures from the unstructured single-stranded DNA conformations. PBP2 downregulates BCL-2 gene expression in cancer cells.
T23858 WCK-5153 WCK 5153,WCK5153 Antibacterial
WCK-5153 is an enhancer of β-Lactamase and an inhibitor of PBP2 with antimicrobial activities against Pseudomonas aeruginosa. WCK-5153 can be used in studies about the treatment of serious infections caused by highly dru...
T38941 FPI-1523 sodium Endogenous Metabolite , Antibacterial
FPI-1523 sodium, a derivative of avibactam, is a potent β-lactamase inhibitor with K d s of 4 nM and 34 nM for CTX-M-15 and OXA-48, respectively.FPI-1523 sodium inhibited PBP2 with an IC 50 of 3.2 μM.FPI-1523 sodium has ...
T21369 Mecillinam Amdinocillin,Mecillinamum,Hexacillin,Coactin,Penicillin HX Antibacterial
Mecillinam (Hexacillin), an extended-spectrum penicillin antibiotic, is considered to be active against Gram-negative bacteria by binding specifically to penicillin-binding protein 2 (PBP2). It is used primarily to treat...
T13395L Zidebactam WCK-5107 Antibacterial
Zidebactam (WCK-5107) is an effective β-lactamase inhibitor. Zidebactam also is a penicillin-binding protein2 inhibitor (IC50: 0.26 μg/mL).
T13395 Zidebactam sodium salt WCK-5107 sodium salt Others
Zidebactam sodium salt is a potent inhibitor of β-lactamase, and also is an inhibitor of penicillin-binding protein2 (PBP2)(IC50 of 0.26 μg/mL).
T38940 FPI-1523
FPI-1523, a derivative of Avibactam, is a potent inhibitor of β-lactamase enzymes. It has Kd values of 4 nM and 34 nM for CTX-M-15 and OXA-48, respectively. Additionally, FPI-1523 inhibits PBP2 with an IC50 of 3.2 μM and...
T61204 FPI-1465
FPI-1465 is a dual inhibitor of serine-β-Lactamases and Penicillin-binding proteins (PBPs), demonstrating inhibition of PBP2 with an IC50 of 1.0 μg/mL. Additionally, it exhibits activity against β-lactamase CTX-M-15 and ...
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